Bioavailability and Dosing of a Monosaccharide Supplement in Adults

NCT00782392 | Completed

• 1 other identifier: 45092
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

We are developing an oral supplement of carbohydrates to be added to infant formulas in order to improve brain development, immune function, and overall health of infants and children. After a careful review of what is known about these sugars, there is very little information regarding their use in infants and children, although there is some information in adults and animals. Many of these sugars have been used in a glyco-nutritional supplement in adults and children, with minimal or no reported side effects. We are developing a custom blend of important individual sugars, and need information regarding their dosing and blood concentrations following oral intake of the carbohydrate supplement. Timed blood samples following the carbohydrate supplement will provide us with a better understanding of the most effective dose and the metabolism of these sugars in adults. This will give us the preliminary information we need for developing an oral supplement of special sugars that can be added to infant formulas to help improve brain development and immune function in infants and children.

Conditions

Healthy Males

Keywords

Nutrition; Infant Formula

Eligibility Criteria

• Age: 18 Years - 28 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy Caucasian Males

You may qualify if:

• Caucasian (non-hispanic)
• Male
• Age 18-28
• Regularly eat breakfast
• Healthy
• BMI within normal limits (18.5 - 24.9)
• English speaking

You may not qualify if:

• History of smoking, more than occasional alcohol use, or drug use.
• Chronic medical diagnosis
• Medications that may interfere with the study

Sponsors & Collaborators

• Arkansas Children's Hospital Research Institute: lead
• University of Arkansas: collaborator
• United States Department of Agriculture (USDA): collaborator

Study Sites (1)

Arkansas Children's Nutrition Center

Little Rock, Arkansas, 72202, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Plasma

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 29, 2008
• First Posted: October 31, 2008
• Study Start: January 1, 2007
• Primary Completion: June 1, 2007
• Last Updated: May 18, 2011

Record last verified: 2011-05

Locations

US (1)