Walking, Spontaneous Physical Activity and Lipid Oxidation After Dietary Treatment of Obesity

NCT00775970 | Unknown

• 1 other identifier: PHRI07-DJ APS
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine whether walking exercise after dietary treatment of obesity is associated with a decrease of the daily spontaneous physical activity and\\or with an increase of the time spent in sedentary activities. Our hypothesis is that the practice of walking as an exercise during the phase of weight stability following the dietary treatment of obesity leads to a reduction of spontaneous physical activity and\\or to an increase in the time spent in sedentary activities.

Conditions

Obesity

Keywords

Obesity; Weight loss maintenance; Spontaneous physical activity; Lipid oxydation; Walking

Outcome Measures

Primary Outcomes (1)

• Daily time of moderate physical activity, inactivity and total physical activity measured by a portable monitor of physical activity

  10 weeks

Secondary Outcomes (1)

• Daily energy expenditure and respiratory quotient during a stay in a respiration chamber

  10 weeks

Interventions

walking activity BEHAVIORAL

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Women from 18 to 50 year-old
• In phase of weight stability
• BMI\<40kg/m²

You may not qualify if:

• History of bariatric surgery
• Diabetes
• Suspicion of obstructive sleep apnea syndrome

Sponsors & Collaborators

• University Hospital, Tours: lead

Study Sites (1)

Service de Médecine Interne - Nutrition / CHRU de Tours

Tours, 37044, France

RECRUITING

Related Publications (11)

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  PMID: 12972441 BACKGROUND

• Fogelholm M, Kukkonen-Harjula K. Does physical activity prevent weight gain--a systematic review. Obes Rev. 2000 Oct;1(2):95-111. doi: 10.1046/j.1467-789x.2000.00016.x.

  PMID: 12119991 BACKGROUND

• Froidevaux F, Schutz Y, Christin L, Jequier E. Energy expenditure in obese women before and during weight loss, after refeeding, and in the weight-relapse period. Am J Clin Nutr. 1993 Jan;57(1):35-42. doi: 10.1093/ajcn/57.1.35.

  PMID: 8416662 BACKGROUND

• Jequier E, Schutz Y. Long-term measurements of energy expenditure in humans using a respiration chamber. Am J Clin Nutr. 1983 Dec;38(6):989-98. doi: 10.1093/ajcn/38.6.989.

  PMID: 6650455 BACKGROUND

• Kraemer WJ, Volek JS, Clark KL, Gordon SE, Incledon T, Puhl SM, Triplett-McBride NT, McBride JM, Putukian M, Sebastianelli WJ. Physiological adaptations to a weight-loss dietary regimen and exercise programs in women. J Appl Physiol (1985). 1997 Jul;83(1):270-9. doi: 10.1152/jappl.1997.83.1.270.

  PMID: 9216973 BACKGROUND

• Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science. 1999 Jan 8;283(5399):212-4. doi: 10.1126/science.283.5399.212.

  PMID: 9880251 BACKGROUND

• Levine JA, Schleusner SJ, Jensen MD. Energy expenditure of nonexercise activity. Am J Clin Nutr. 2000 Dec;72(6):1451-4. doi: 10.1093/ajcn/72.6.1451.

  PMID: 11101470 BACKGROUND

• Nicklas BJ, Rogus EM, Goldberg AP. Exercise blunts declines in lipolysis and fat oxidation after dietary-induced weight loss in obese older women. Am J Physiol. 1997 Jul;273(1 Pt 1):E149-55. doi: 10.1152/ajpendo.1997.273.1.E149.

  PMID: 9252491 BACKGROUND

• van Aggel-Leijssen DP, Saris WH, Hul GB, van Baak MA. Short-term effects of weight loss with or without low-intensity exercise training on fat metabolism in obese men. Am J Clin Nutr. 2001 Mar;73(3):523-31. doi: 10.1093/ajcn/73.3.523.

  PMID: 11237927 BACKGROUND

• van Aggel-Leijssen DP, Saris WH, Wagenmakers AJ, Hul GB, van Baak MA. The effect of low-intensity exercise training on fat metabolism of obese women. Obes Res. 2001 Feb;9(2):86-96. doi: 10.1038/oby.2001.11.

  PMID: 11316351 BACKGROUND

• Zurlo F, Lillioja S, Esposito-Del Puente A, Nyomba BL, Raz I, Saad MF, Swinburn BA, Knowler WC, Bogardus C, Ravussin E. Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. Am J Physiol. 1990 Nov;259(5 Pt 1):E650-7. doi: 10.1152/ajpendo.1990.259.5.E650.

  PMID: 2240203 BACKGROUND

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• David JACOBI, MD

  Service de médecine Interne-Nutrition

  PRINCIPAL INVESTIGATOR

Central Study Contacts

David JACOBI, MD

CONTACT

+33247474727; jacobi@med.univ-tours.fr

Pascaline RAMEAU, CRA

CONTACT

+33247366249; rameau@med.univ-tours.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 17, 2008
• First Posted: October 20, 2008
• Study Start: May 1, 2008
• Last Updated: October 20, 2008

Record last verified: 2008-10

Locations

FR (1)