NCT00773682

Brief Summary

Objective To assess both the short-term and the long term effectiveness of spa therapy in patients with primary hand osteoarthritis (OA) in a single blind, prospective controlled, randomized trial.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Jun 2008

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 15, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 16, 2008

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2009

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2010

Completed
Last Updated

November 17, 2011

Status Verified

September 1, 2008

Enrollment Period

1.3 years

First QC Date

October 15, 2008

Last Update Submit

November 16, 2011

Conditions

Keywords

osteoarthritishandsmud-packs therapybalneotherapyOsteoarthritis of the hands

Outcome Measures

Primary Outcomes (1)

  • Algofunctional state and quality of life

    two weeks, three , six, nine and twelve months

Secondary Outcomes (1)

  • Consumption of symptomatic drugs and tolerability

    two weeks, three, six, nine and twelve months

Interventions

Patients will be treated with local mud-pack application on the hands for 20 minutes and thermal-mineral bath once a day for 15 days.

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients suffering from osteoarthritis of the hands according to the ACR criteria

You may not qualify if:

  • Patients suffering from any other rheumatological disease other than osteoarthritis
  • Patients that have been treated with mud-pack therapy and balneotherapy in the last 9 months
  • Contraindications to mud-packs and balneotherapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rheumatology Unit Azienda Ospedaliera Universitaria Senese

Siena, Siena, 53100, Italy

Location

Related Publications (3)

  • Fioravanti A, Perpignano G, Tirri G, Cardinale G, Gianniti C, Lanza CE, Loi A, Tirri E, Sfriso P, Cozzi F. Effects of mud-bath treatment on fibromyalgia patients: a randomized clinical trial. Rheumatol Int. 2007 Oct;27(12):1157-61. doi: 10.1007/s00296-007-0358-x. Epub 2007 May 23.

    PMID: 17520260BACKGROUND
  • Cantarini L, Leo G, Giannitti C, Cevenini G, Barberini P, Fioravanti A. Therapeutic effect of spa therapy and short wave therapy in knee osteoarthritis: a randomized, single blind, controlled trial. Rheumatol Int. 2007 Apr;27(6):523-9. doi: 10.1007/s00296-006-0266-5. Epub 2006 Nov 15.

    PMID: 17106661BACKGROUND
  • Fioravanti A, Valenti M, Altobelli E, Di Orio F, Nappi G, Crisanti A, Cantarini L, Marcolongo R. Clinical efficacy and cost-effectiveness evidence of spa therapy in osteoarthritis. The results of "Naiade" Italian Project. Panminerva Med. 2003 Sep;45(3):211-7.

    PMID: 14618120BACKGROUND

MeSH Terms

Conditions

Osteoarthritis

Interventions

Balneology

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

Therapeutics

Study Officials

  • Antonella Fioravanti, md

    Rheumatology Unit- Azienda Ospedaliera Universitaria Senese-siena

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
medical doctor

Study Record Dates

First Submitted

October 15, 2008

First Posted

October 16, 2008

Study Start

June 1, 2008

Primary Completion

September 1, 2009

Study Completion

January 1, 2010

Last Updated

November 17, 2011

Record last verified: 2008-09

Locations