NCT00764400

Brief Summary

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable stroke

Timeline
Completed

Started Aug 2008

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2008

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 30, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 2, 2008

Completed
4.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2013

Completed
Last Updated

April 6, 2018

Status Verified

April 1, 2018

Enrollment Period

4.8 years

First QC Date

September 30, 2008

Last Update Submit

April 4, 2018

Conditions

Keywords

aphasiaanomiaspeech therapyrehabilitation

Outcome Measures

Primary Outcomes (1)

  • Daily Probe Picture Naming

    daily probes from three times per week for up to 3 months and one month posttreatment

Secondary Outcomes (3)

  • Western Aphasia Battery

    pre-treatment and at treatment completion

  • Boston Naming Test

    pretreatment and at treatment completion

  • Discourse Sample

    pre-treatment and at treatment completion

Study Arms (2)

Errorless Naming Treatment

EXPERIMENTAL
Behavioral: Word Retrieval Treatments for Aphasia

Verbal+Gestural Facilitation

EXPERIMENTAL
Behavioral: Word Retrieval Treatments for Aphasia

Interventions

Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

Errorless Naming TreatmentVerbal+Gestural Facilitation

Eligibility Criteria

Age21 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • left hemisphere stroke \>4 months earlier
  • aphasia with word retrieval impairments
  • \>21 years of age right handed
  • speaker of English as the preferred language
  • \>6 grade education

You may not qualify if:

  • history of developmental learning difficulties
  • history of prior neurological illnesses
  • chronic medical illnesses that restrict participation in speech therapy
  • alcohol or drug dependence
  • severe uncorrected impairments of vision or hearing

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Old Dominion University Speech and Hearing Clinic

Norfolk, Virginia, 23529, United States

Location

MeSH Terms

Conditions

StrokeAphasiaAnomiaCommunication Disorders

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesSpeech DisordersLanguage DisordersNeurobehavioral ManifestationsNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodevelopmental DisordersMental Disorders

Study Officials

  • Anastasia M Raymer, PhD

    Old Dominion University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Communications Disorders & Special Education

Study Record Dates

First Submitted

September 30, 2008

First Posted

October 2, 2008

Study Start

August 1, 2008

Primary Completion

June 1, 2013

Study Completion

July 1, 2013

Last Updated

April 6, 2018

Record last verified: 2018-04

Locations