Randomized Trial of Prehospital Tropin Levels in Acute Coronary Syndrome (ACS)

NCT00764205 | Unknown

• 1 other identifier: 20070224
• Study Type: observational
• Target: 1,200
• Locations: 1 country
• Sites: 1

Brief Summary

This study randomizes patients seen by Redmond Medic One into a control arm and a study arm when they present with acute coronary syndrome and have non-contributory ECG's (i.e.non-STEMI). The control group is treated normally and delivered to the receiving hospital. The study group is treated normally as well, however troponin measurements are made using an i-STAT blood analyzer prior to hospital arrival. The results are presented to the receiving physician. Door-to-reperfusion time is monitored for both groups.

Conditions

Acute Coronary Syndrome

Keywords

ACS; non STEMI; ECG troponin; iSTAT; Acute coronary syndrome without ST-segment elevation

Outcome Measures

Primary Outcomes (1)

• Decrease door-to-reperfusion time for patients with non-STEMI's by measuring troponin levels prior to hospital arrival

  3-4 years

Study Arms (2)

Study Group

Troponin measured prior to hospital arrival

Control Group

Patients transported to hospital without troponin measurements enroute

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients seen and treated by Redmond Fire Department Medic One.

You may qualify if:

• Over years of age
• ACS without ST-segment elevation
• Patient being transported to one of two participating hospitals

You may not qualify if:

• Less then 18 years of age.
• Post cardiac arrest.
• ACS with ST-segment elevation.

Sponsors & Collaborators

• Redmond Fire Department Medic One: lead
• Medic One Foundation: collaborator

Study Sites (1)

Redmond Fire Department Medic One Units

-Mobile Units in King County-, Washington, 98052, United States

Location

MeSH Terms

Conditions

Acute Coronary Syndrome; Non-ST Elevated Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Myocardial Infarction; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Officials

• James P Jordan, BS, MS, MICP

  Redmond Fire Department Medic One

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV

Study Record Dates

• First Submitted: September 30, 2008
• First Posted: October 1, 2008
• Study Start: November 1, 2006
• Primary Completion: November 1, 2009
• Study Completion: November 1, 2010
• Last Updated: October 1, 2008

Record last verified: 2008-09

Locations

US (1)