The Effect of Providing Free Samples of Generic Cardiovascular Medications to Physicians
SAMPLES
A Study Assessing the Effect of Cardiovascular Medications Provided as Low-cost, Evidence-based Generic Samples
2 other identifiers
interventional
660
1 country
1
Brief Summary
In this randomized controlled trial, we will provide primary care physicians with free samples of highly effective generic cardiovascular medications. We will test whether this intervention will stimulate cost-effective prescribing, reducing drug costs and improving adherence to essential cardiovascular medications.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable hypertension
Started Dec 2010
Shorter than P25 for not_applicable hypertension
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 26, 2008
CompletedFirst Posted
Study publicly available on registry
September 30, 2008
CompletedStudy Start
First participant enrolled
December 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2011
CompletedMay 5, 2010
May 1, 2010
4 months
September 26, 2008
May 3, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Percentage of prescriptions filled for generic medications
6 months after receipt of samples
Patient adherence - Amount of prescriptions actually filled (Proportion of Days Covered) within each class in the first year of use of an anti-hypertensive or lipid-lowering medication
in the year subsequent to patient initiation of an anti-hypertensive or lipid-lowering medication
Secondary Outcomes (2)
The sum of medication costs for all prescriptions used to treat either hypertension or hypercholesterolemia.
The year before and the year after provision of samples
Guideline adherence - Proportion of patients who received first-line anti-hypertensive medications suggested by JNC-VII when medications are initiated.
In the 6 months after receipt of samples
Study Arms (2)
receipt of free generic samples
EXPERIMENTALusual prescribing
NO INTERVENTIONInterventions
Free samples of generic hydrochlorothiazide (12.5 mg tabs) and simvastatin (20 mg tabs)
Eligibility Criteria
You may qualify if:
- Primary care physicians receiving an existing academic detailing program in Pennsylvania
You may not qualify if:
- Those with administrative policies stating they do not accept free samples
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Brigham and Women's Hospital
Boston, Massachusetts, 02120, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
William H Shrank, MD
Brigham and Women's Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 26, 2008
First Posted
September 30, 2008
Study Start
December 1, 2010
Primary Completion
April 1, 2011
Study Completion
April 1, 2011
Last Updated
May 5, 2010
Record last verified: 2010-05