NCT00745758

Brief Summary

Extensive research has shown that the big event that leads to the initiation of vasospasm is the release of oxyhemoglobin (blood breakdown product).Depletion of NO synthase (19,20,21) was also noted after SAH.CSF is produced from choroid plexus in the ventricle. If the SAH is too dense, the blood in the subarachnoid space will not easy to be washed out.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2008

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 31, 2008

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 3, 2008

Completed
Last Updated

September 3, 2008

Status Verified

September 1, 2008

First QC Date

August 31, 2008

Last Update Submit

September 2, 2008

Conditions

Subarachnoid HemorrhageVasospasm, Intracranial

Keywords

SAH, vasospasm, ADMA

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patient of spontaneous SAH

You may qualify if:

  • Aneurysmal rupture with SAH

You may not qualify if:

  • Bleeding tendency,
  • Large ICH with impending herniation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

devision of neurosurgery, National taiwan university hospital

Taipei, 112, Taiwan

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

CSF

MeSH Terms

Conditions

Subarachnoid HemorrhageVasospasm, Intracranial

Condition Hierarchy (Ancestors)

Intracranial HemorrhagesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesHemorrhagePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Kuo-Chuan Wang, MD

    NTUH

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Kuo-Chuan Wang, MD

CONTACT

886-223123456wang081466@yahoo.com.tw

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 31, 2008

First Posted

September 3, 2008

Study Start

May 1, 2008

Study Completion

September 1, 2008

Last Updated

September 3, 2008

Record last verified: 2008-09

Locations

TW(1)