NCT00740558

Brief Summary

Background The purpose of this study was to examine the heart rate variability (HRV) in the presence or the absence of pain in the lower back (L5), while receiving chiropractic care. Methods A total of 53 healthy participants were randomly assigned to a control, 2 treatment or 2 sham groups (n = 10 per group). Participants underwent an eight-minute acclimatizing period. The HRV tachygram (RR interval) data were recorded directly into a Suunto watch (model T6). The investigators analyzed the five minute pre-treatment and post treatments intervals. The spectral analysis of the tachygram was performed with the Kubios Software (University of Kuopio, Finland).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
53

participants targeted

Target at P25-P50 for not_applicable low-back-pain

Timeline
Completed

Started Jul 2004

Typical duration for not_applicable low-back-pain

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2004

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2006

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

August 22, 2008

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 25, 2008

Completed
Last Updated

August 27, 2008

Status Verified

August 1, 2008

Enrollment Period

2 years

First QC Date

August 22, 2008

Last Update Submit

August 26, 2008

Conditions

Keywords

HRVActivatorChiropracticVLFHFLFLF/HF

Outcome Measures

Primary Outcomes (1)

  • Mean R-R interval, the number of pairs of adjacent NN intervals differing by more than 50 ms, and the proportion of NN intervals differing by more than 50 ms the very low frequency, the low frequency, the high frequency, the LF/HF ratio

    Pre and post measurements of one intervention

Study Arms (2)

1

ACTIVE COMPARATOR

Two groups received a traditional chiropractic adjustment of the lumbar 5 and the other group received a manually assisted mechanical force adjustment of the lumbar 5.

Procedure: Activator methods techniqueProcedure: Traditional chiropractic adjustment

2

SHAM COMPARATOR

The investigators had two groups, one for each chiropractic technique used in the research project and we had a control group

Procedure: Activator methods techniqueProcedure: Traditional chiropractic adjustment

Interventions

Chiropractic adjustment by a manually assisted mechanical force

Also known as: Activator methods
12

Lumbar roll according to the Diversified technique of chiropractic adjusting

Also known as: Lumbar roll
12

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Acute low back pain (pain group)
  • Maintenance care for the pain free group and the control group

You may not qualify if:

  • For the control group (pain)
  • For the non pain group pain

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Chiro-clinique Richard Roy

LaSalle, Quebec, H8N 1X7, Canada

Location

Dr Richard Roy et Dr Fafard

LaSalle, Quebec, H8N1X7, Canada

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Richard A Roy, DCMScPhD(c)

    Université du Québec a Montréal

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 22, 2008

First Posted

August 25, 2008

Study Start

July 1, 2004

Primary Completion

July 1, 2006

Study Completion

July 1, 2006

Last Updated

August 27, 2008

Record last verified: 2008-08

Locations