Interventions to Increase HBV Vaccinations in Sexually Transmitted Disease (STD) Clinics
2 other identifiers
interventional
1,747
1 country
2
Brief Summary
The goal of this study is to evaluate two sets of interventions to increase acceptance of hepatitis B virus (HBV) vaccination in patients attending sexually transmitted disease (STD) clinics. The 1st set of interventions, with 3 levels, is based on message framing. The 3 levels are: 1. information only; 2. gain-framed message; and 3. loss-framed message. The 2nd set of interventions, with 2 levels, involves how the vaccine is recommended by the health care provider. The 2 levels are: 1. HBV vaccine offered; and 2. HBV vaccine recommended. The outcome of interest is1st dose acceptance.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2003
Longer than P75 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2003
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2007
CompletedFirst Submitted
Initial submission to the registry
August 20, 2008
CompletedFirst Posted
Study publicly available on registry
August 22, 2008
CompletedResults Posted
Study results publicly available
October 16, 2017
CompletedNovember 9, 2018
November 1, 2018
4 years
August 20, 2008
April 6, 2017
November 7, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mean Number of Doses of HBV Vaccine Received
Mean Number of HBV vaccine doses received over an 8-month period, including the clinic visit. Count values ranged from 0 to 3 doses.
Day of research visit with 8 month follow-up
Study Arms (6)
Non-Framed-Offered
EXPERIMENTALNon-Framed, Information Only Condition. Vaccine Offered.
Non-Framed-Recommended
EXPERIMENTALNon-Framed, Information Only Condition. Vaccine Recommended.
Gain-Framed-Offered
EXPERIMENTALGain-Framed Intervention emphasizes the benefits associated with receiving HBV vaccine. Vaccine Offered.
Gain-Framed-Recommended
EXPERIMENTALGain-Framed Intervention emphasizes the benefits associated with receiving HBV vaccine. Vaccine Recommended.
Loss-Framed-Offered
EXPERIMENTALLoss-Framed Intervention emphasizes the risks associated with not receiving HBV vaccine. Vaccine Offered.
Loss-Framed-Recommended
EXPERIMENTALLoss-Framed Intervention emphasizes the risks associated with not receiving HBV vaccine. Vaccine Recommended.
Interventions
Subjects received information only and are offered the vaccine.
Subjects receive information only and are recommended the vaccine.
Subjects receive gain-framed messages and are offered the vaccine.
Subjects receive gain-framed messages and are recommended the vaccine.
Subjects receive loss-framed messages and are offered the vaccine.
Subjects receive loss-framed messages and are recommended the vaccine.
Eligibility Criteria
You may qualify if:
- Age 18 and older males and females
- No prior self-reported history of HBV immunization or infection
- Fluent in English
- Not known to be HIV positive.
You may not qualify if:
- Under age 18
- Received any prior HBV vaccination
- Prior infection of Hepatitis B
- Unable to read or comprehend the English language
- HIV positive
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Chicago Department of Public Health
Chicago, Illinois, 60604, United States
Bell Flower Clinic
Indianapolis, Indiana, 46202, United States
Related Publications (2)
Cox AD, Cox D, Zimet G. Promoting prevention and early detection: The impact of message framing, product function and perceived product risk. J Marketing 2006;70:79-91.
RESULTKasting ML, Head KJ, Cox D, Cox AD, Zimet GD. The effects of message framing and healthcare provider recommendation on adult hepatitis B vaccination: A randomized controlled trial. Prev Med. 2019 Oct;127:105798. doi: 10.1016/j.ypmed.2019.105798. Epub 2019 Aug 9.
PMID: 31404569DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Dr. Gregory Zimet
- Organization
- Indiana University
Study Officials
- PRINCIPAL INVESTIGATOR
Gregory D Zimet, PhD
Indiana University
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- FACTORIAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Pediatrics & Clinical Psychology
Study Record Dates
First Submitted
August 20, 2008
First Posted
August 22, 2008
Study Start
June 1, 2003
Primary Completion
June 1, 2007
Study Completion
October 1, 2007
Last Updated
November 9, 2018
Results First Posted
October 16, 2017
Record last verified: 2018-11
Data Sharing
- IPD Sharing
- Will not share