Surveillance and Medical Help for HIV-infected Intravenous Drug Users in and Out of Prison

NCT00739258 | Completed

• 1 other identifier: KMUH-IRB-970077
• Study Type: observational
• Target: 700
• Locations: 1 country
• Sites: 1

Brief Summary

It is difficult to detect the intestinal protozoal infections among the HIV-infected persons or travelers diarrhea by using the traditional microscopy or staining methods. The purpose of this study aimed at finding out the appropriate diagnostic methods and the infection rate of the intestinal protozoa, including the Entamoeba, Cryptosporidium and Giardia among the HIV-infected persons by using the antigen detection method and biological method. The investigators also tried to analyze the associated HIV infection status and sexual transmitted diseases (STD) including Gonorrhea, Chlamydial trachomatis, Syphilis, Genital warts and Herpes simplex virus in this study. The study will collect the blood, urine and stool samples from 200 intravenous drug user (IDU) with HIV-infected in the prisons, 400 intravenous drug user (IDU) without HIV infected and 100 intravenous drug user (IDU) with HIV infected receiving methadone maintenance treatment.

Conditions

HIV Infections

Keywords

HIV-infected person; Entamoeba; Cryptosporidium; Giardia; ELISA; PCR; IDU; Gonorrhea; Chlamydial trachomatis; Syphilis; Genital warts; Herpes simplex virus

Study Arms (3)

HIDU

intravenous drug user (IDU) with HIV infected

IDU

intravenous drug user (IDU) without HIV

MH

persons receiving methadone maintenance treatment

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The samples are obtained from Kaohsiung prison, Kaohsiung women's prison, Pingtung prison and the Kaohsiung Medical University Chung-Ho Memorial Hospital in Kaohsiung, Taiwan.

You may qualify if:

• Clinical diagnosis of HIV
• Receiving Methadone Maintenance Treatment
• intravenous drug user (IDU)

Sponsors & Collaborators

• Kaohsiung Medical University Chung-Ho Memorial Hospital: lead
• Centers for Disease Control and Prevention: collaborator

Study Sites (1)

Kaoshing Medical University Chung-Ho Memorial Hospital

Kaohsiung City, Taiwan

Location

MeSH Terms

Conditions

HIV Infections; Giardiasis; Gonorrhea; Syphilis; Condylomata Acuminata; Herpes Simplex

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Intestinal Diseases, Parasitic; Parasitic Diseases; Protozoan Infections; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Neisseriaceae Infections; Gram-Negative Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Sexually Transmitted Diseases, Bacterial; Treponemal Infections; Spirochaetales Infections; Papillomavirus Infections; DNA Virus Infections; Warts; Skin Diseases, Viral; Tumor Virus Infections; Skin Diseases, Infectious; Skin Diseases; Skin and Connective Tissue Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Herpesviridae Infections

Study Design

• Study Type: observational
• Observational Model: COHORT
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 19, 2008
• First Posted: August 21, 2008
• Study Start: April 1, 2008
• Primary Completion: December 1, 2010
• Study Completion: December 1, 2010
• Last Updated: January 23, 2012

Record last verified: 2011-12

Locations

TW (1)