Sponsor study identifier
observational
108
1 country
1
Study Start
May 2005
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
July 2006
Actual (reported)Study Completion
December 2006
Actual (reported)Vitrectomy is one of the major treatment methods for complications of diabetic retinopathy. As surgical techniques and instruments improve, high anatomical success may be achieved; however, functional results are less favorable. Despite attached retina, postoperative visual function may be affected by various macular and disc abnormalities. Major changes include optic atrophy, atrophic retina, poor macular perfusion, and structural alternations of the macula. Funduscopy, fluorescein angiography, and, more recently, optical coherence tomography (OCT) can be used to detect and document these alterations. Although fluorescein angiography is valuable in the assessment of various macular lesions as well as retinal vascular abnormalities, its usefulness in evaluating macular changes is limited in eyes that have undergone diabetic vitrectomy. The quality of the images may be compromised by mild diffuse hyperfluorescence in the posterior pole in middle and late phase angiography, which obscures capillary detail and subtle macular changes. Furthermore, quantification of changes may not be possible. Recently, optical coherence tomography has become very useful for the detection of vitreomacular abnormalities. The examination is noninvasive, can qualify the changes and detect subtle abnormalities not evident with other imaging studies. In this study, OCT was applied to investigate how common macular structure abnormalities are present after surgery for complications of diabetic retinopathy, and how they may affect visual prognosis.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2006
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2005
Date type not reportedThis date has not been verified as actual or estimated.
July 2006
Actual (reported)December 2006
Actual (reported)August 14, 2008
Actual (reported)August 18, 2008
Actual (reported)Macular appearance
Six months
Post-operation best-corrected visual acuity
Six months
Proliferative diabetic retinopathy
Department of Ophthalmology, National Taiwan University Hospital
Taipei, 100, Taiwan
Chung-May Yang, MD
National Taiwan University Hospital
108 participants (actual enrollment reported by the registry).
First Submitted
August 14, 2008
First Posted
August 18, 2008
Study Start
May 2005
Date type not reportedThis date has not been verified as actual or estimated.
Macular Tractional Retinoschisis in Proliferative Diabetic Retinopathy
Contact the study team to confirm eligibility.
Primary Completion
July 2006
Actual (reported)Study Completion
December 2006
Actual (reported)Last Updated
August 18, 2008
Record last verified: 2006-07
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Source: ClinicalTrials.gov.
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