BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients
BICUK
1 other identifier
observational
51
1 country
1
Brief Summary
The purpose of this study is to find out whether acute renal failure is associated with BK virus reactivation in postoperative/posttraumatic critically ill patients with severe SIRS/sepsis and shock.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Aug 2008
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2008
CompletedFirst Submitted
Initial submission to the registry
August 15, 2008
CompletedFirst Posted
Study publicly available on registry
August 18, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2012
CompletedDecember 4, 2015
December 1, 2015
4 years
August 15, 2008
December 2, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Association between BK virus reactivation and acute renal dysfunction
Daily monitoring of acute renal failure, first day of acute renal dysfunction, first days on hemodiafiltration, first day after hemodiafiltration, before demission from intensive care unit or death.
Secondary Outcomes (1)
Pattern of biomarkers and surface markers on leukocytes.
First day of acute renal dysfunction, first days on hemodiafiltration, first day after hemodiafiltration, before demission from intensive care unit or death.
Study Arms (2)
Patients with non-septic shock
Postoperative/posttraumatic surgical critically ill patients with non-septic shock with threatening acute renal failure
Patients with septic shock
Postoperative/posttraumatic surgical critically ill patients with septic shock with threatening acute renal failure
Eligibility Criteria
Postoperative/posttraumatic critically ill patients admitted to the intensive care unit
You may qualify if:
- Critically ill, postoperative/posttraumatic patients with threatening acute renal failure
You may not qualify if:
- Life expectancy \< 24 hours
- Participation in other trials
- Known or suspected pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Ulmlead
- University of Wuerzburgcollaborator
Study Sites (1)
Clinic of Anesthesiology
Ulm, 89070, Germany
Related Publications (1)
Nass M, Weissbrich B, Huber M, Schneider EM, Weiss M. BK viremia in critically ill surgical patients with hemorrhagic or septic shock. BMC Res Notes. 2012 Feb 16;5:100. doi: 10.1186/1756-0500-5-100.
PMID: 22339896RESULT
Related Links
Biospecimen
Whole blood, serum, white blood cells; urine
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Manfred Weiss, MD, MBA
University Hospital Ulm
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor, MD, MBA
Study Record Dates
First Submitted
August 15, 2008
First Posted
August 18, 2008
Study Start
August 1, 2008
Primary Completion
August 1, 2012
Study Completion
December 1, 2012
Last Updated
December 4, 2015
Record last verified: 2015-12