NCT00732342

Brief Summary

310 alcohol abusing or dependent patients beginning intensive outpatient day treatment at community-based clinics will be randomly assigned to one of four conditions: (a) standard treatment as usual (ST) at the clinic without contingency management (CM); (b) standard treatment with contingency management for 12 weeks with a 0.5 probability of winning prizes for each negative sample submitted; (c) standard treatment with contingency management for 24 weeks with a 0.34 probability of winning prizes for each negative sample submitted; or (d) standard treatment with contingency management for 24 weeks with a 0.5 probability of winning prizes for each negative sample submitted. We expect that contingency management will decrease alcohol use to a greater extent than non-contingency management treatment, and that availability of contingency management for 24 weeks may result in longer term benefits than 12 week exposure to contingency management. This study will be the first to evaluate the effects of probability of winning prizes on response to contingency management.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
310

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2008

Longer than P75 for not_applicable

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2008

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

August 7, 2008

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 12, 2008

Completed
6.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

April 9, 2019

Status Verified

April 1, 2019

Enrollment Period

7.2 years

First QC Date

August 7, 2008

Last Update Submit

April 5, 2019

Conditions

Alcohol Abuse

Keywords

Alcohol AbuseContingency ManagementTreatment Duration

Outcome Measures

Primary Outcomes (1)

  • longest duration of negative breath samples submitted

    active phase and throughout follow-up phase

Secondary Outcomes (1)

  • subjective reports of alcohol use

    baseline and each follow-up

Study Arms (4)

1

NO INTERVENTION

Standard Treatment

2

EXPERIMENTAL

Standard Treatment with Contingency Management for 12 weeks with a 0.5 probability of winning prizes for each negative sample submitted

Behavioral: Contingency Management

3

EXPERIMENTAL

Standard Treatment with Contingency Management for 24 weeks with a 0.34 probability of winning prizes for each negative sample submitted

Behavioral: Contingency Management

4

EXPERIMENTAL

Standard Treatment with Contingency Management for 24 weeks with a 0.5 probability of winning prizes for each negative sample submitted

Behavioral: Contingency Management

Interventions

Contingency ManagementBEHAVIORAL

Prizes given for targeted behavior of abstinence

234

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \> 18 years
  • current DSM-IV diagnosis of alcohol abuse or dependence
  • willing to sign informed consent and able to pass an informed consent quiz

You may not qualify if:

  • serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk) on the basis of history or medical examination
  • current DSM-IV diagnosis of opioid dependence
  • in recovery from pathological gambling

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Prospect House

Bridgeport, Connecticut, 06604, United States

Location

Alcohol and Drug Recovery Centers, Inc.

Hartford, Connecticut, 06112, United States

Location

The Hospital of Central Connecticut at New Britain General

New Britain, Connecticut, 06050, United States

Location

Morris Foundation

Waterbury, Connecticut, 06702, United States

Location

Carlson Recovery Center

Springfield, Massachusetts, 01199, United States

Location

MeSH Terms

Conditions

Alcoholism

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Study Officials

  • Nancy M Petry, Ph.D.

    UConn Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 7, 2008

First Posted

August 12, 2008

Study Start

February 1, 2008

Primary Completion

May 1, 2015

Study Completion

May 1, 2015

Last Updated

April 9, 2019

Record last verified: 2019-04

Locations

US(5)