NCT00731315

Brief Summary

Our study aims to test the utility of computer-assisted treatment for uncomplicated, recurrent urinary tract infections (UTIs) for women receiving care in safety net health care facilities. As of November 2009, we are also testing the utility of computer-assisted treatment for certain types of complicated cystitis (i.e. women with voiding symptoms and one of the following complicating symptoms: fever, flank pain, or symptoms greater than 7 days).

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2008

Typical duration for not_applicable

Geographic Reach
1 country

5 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2008

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

August 5, 2008

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 11, 2008

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2011

Completed
Last Updated

March 6, 2015

Status Verified

March 1, 2015

Enrollment Period

2.9 years

First QC Date

August 5, 2008

Last Update Submit

March 5, 2015

Conditions

Keywords

UTIKioskComputer Assisted Carecystitis

Outcome Measures

Primary Outcomes (1)

  • The proportion of subjects with treatment failure or relapse

    21 days

Secondary Outcomes (1)

  • Patient acceptability of treatment by computer

    21 days

Study Arms (4)

Treatment Group 1 - uncomplicated UTI

EXPERIMENTAL

Would receive computer-assisted treatment for a uncomplicated UTI.

Other: Computer-assisted treatment group

Control Group 1

ACTIVE COMPARATOR

Qualified for expedited treatment for uncomplicated cystitis but would receive usual care in the Emergency Department of Community Health Center.

Other: Usual care group

Treatment Group 2 - Complicated Cystitis

EXPERIMENTAL

Would receive expedited treatment for complicated cystitis with longer antibiotic course than the simple UTI patients.

Other: Computer-assisted treatment group

Control Group 2

ACTIVE COMPARATOR

Qualified for expedited treatment for complicated cystitis treatment but would receive usual care in the clinic or emergency department.

Other: Usual care group

Interventions

This group will receive computer-assisted expedited treatment for uncomplicated UTI or complicated cystitis based on their symptoms and past medical history reported on the computer.

Treatment Group 1 - uncomplicated UTITreatment Group 2 - Complicated Cystitis

This group will receive usual care for an uncomplicated UTI or complicated cystitis in the Emergency Department or Community Health Center.

Control Group 1Control Group 2

Eligibility Criteria

Age18 Years - 64 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Female
  • years old

You may not qualify if:

  • Below 18 or Above 64
  • Male
  • New flank pain
  • severe vomiting
  • High blood sugar or diabetes
  • surgery on kidneys
  • chronic kidney disease
  • Previous cancer or chemotherapy
  • HIV or AIDS
  • pregnant or suspected pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

CMC Fresno Emergency Department

Fresno, California, 93701, United States

Location

La Clinica

Oakland, California, 94601, United States

Location

Highland Hospital Emergency Department

Oakland, California, 94602, United States

Location

San Francisco General Hospital - Emergency Department

San Francisco, California, 94110, United States

Location

UCSF Emergency Deparmtent

San Francisco, California, 94143, United States

Location

MeSH Terms

Conditions

Urinary Tract InfectionsCystitis

Condition Hierarchy (Ancestors)

InfectionsUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesUrinary Bladder Diseases

Study Officials

  • Ralph Gonzales, MD

    University of California, San Francsico

    PRINCIPAL INVESTIGATOR
  • John Stein, MD

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR
  • Bradley Frazee, MD

    Alameda County Medical Centers, Highland Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 5, 2008

First Posted

August 11, 2008

Study Start

August 1, 2008

Primary Completion

July 1, 2011

Study Completion

July 1, 2011

Last Updated

March 6, 2015

Record last verified: 2015-03

Locations