NCT00727259

Brief Summary

The current gold standard for treatment of chronic hepatitis C (CHC) patients is with pegylated interferon plus ribavirin. Drug administration accuracy and ease of use will definitely determine treatment effectiveness. This is the idea behind the development and usage of the PegPen. The goal of this study is to determine the satisfaction grade with this novel device.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,995

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2004

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2004

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2008

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

July 30, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 1, 2008

Completed
1 year until next milestone

Results Posted

Study results publicly available

August 6, 2009

Completed
Last Updated

April 29, 2015

Status Verified

April 1, 2015

Enrollment Period

3.5 years

First QC Date

July 30, 2008

Results QC Date

June 18, 2009

Last Update Submit

April 7, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Evaluation of the Satisfaction of the PegPen (PegIntron Preparation and Injection Easiness) Using a Patient Questionnaire Answered at 1 Month and 3 Months

    Patient satisfaction for each item on the questionnaires was rated on a scale from 0 (not satisfied) to 7 (very satisfied).

    The patient was instructed to answer and return by mail the first self-questionnaire after 1 month of treatment and the second one after 3 months of treatment.

Study Arms (1)

Patients with chronic hepatitis C

Adult patients with chronic hepatitis C treated with PegIntron pen/Rebetol.

Biological: Peginterferon alfa-2b (SCH 54031)Drug: Ribavirin (SCH 18908)

Interventions

Peginterferon alfa-2b will be administered according to the products' labeling.

Also known as: PegIntron, PegPen
Patients with chronic hepatitis C

Ribavirin will be administered according to the products' labeling.

Also known as: Rebetol
Patients with chronic hepatitis C

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adult patients with chronic hepatitis C treated with PegIntron pen/Rebetol at sites in France.

You may qualify if:

  • Adult patients with hepatitis C

You may not qualify if:

  • According to the products' labeling.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hepatitis C, Chronic

Interventions

peginterferon alfa-2bRibavirin

Condition Hierarchy (Ancestors)

Hepatitis CBlood-Borne InfectionsCommunicable DiseasesInfectionsHepatitis, Viral, HumanVirus DiseasesFlaviviridae InfectionsRNA Virus InfectionsHepatitis, ChronicHepatitisLiver DiseasesDigestive System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

RibonucleosidesNucleosidesNucleic Acids, Nucleotides, and Nucleosides

Results Point of Contact

Title
Senior Vice President, Global Clinical Development
Organization
Merck Sharp & Dohme Corp.

Study Officials

  • Clinical Director

    Merck Sharp & Dohme LLC

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 30, 2008

First Posted

August 1, 2008

Study Start

October 1, 2004

Primary Completion

April 1, 2008

Study Completion

April 1, 2008

Last Updated

April 29, 2015

Results First Posted

August 6, 2009

Record last verified: 2015-04