320-slice Coronary Computed Tomography (CT) Angiography
Coronary Artery Imaging With 320-slice Computed Tomography
1 other identifier
observational
30
1 country
1
Brief Summary
The primary aim of this study is to determine the potential utility of 320-slice volume-CT for obtaining adequate diagnostic accuracy while at the same time improving image quality compared with previous generations of CT scanners and simultaneously enabling a reduction in both radiation exposure and contrast agent amount required.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Apr 2008
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2008
CompletedFirst Submitted
Initial submission to the registry
July 23, 2008
CompletedFirst Posted
Study publicly available on registry
July 25, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2008
CompletedJune 23, 2011
February 1, 2009
8 months
July 23, 2008
June 21, 2011
Conditions
Eligibility Criteria
Consecutive eligible patients referred to the Charité and scheduled to undergo conventional coronary angiography.
You may qualify if:
- years of age
- sinus rhythm
You may not qualify if:
- prior conventional coronary angiography
- unstable presentation
- coronary artery bypass graft or stent
- pregnancy or breast-feeding
- creatinine \> 2.0 mg per deciliter
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Charité
Berlin, State of Berlin, 10117, Germany
Related Publications (4)
Dewey M, Zimmermann E, Laule M, Rutsch W, Hamm B. Three-vessel coronary artery disease examined with 320-slice computed tomography coronary angiography. Eur Heart J. 2008 Jul;29(13):1669. doi: 10.1093/eurheartj/ehm626. Epub 2008 Feb 7. No abstract available.
PMID: 18263576BACKGROUNDZimmermann E, Dewey M. Whole-heart 320-row computed tomography: reduction of radiation dose via prior coronary calcium scanning. Rofo. 2011 Jan;183(1):54-9. doi: 10.1055/s-0029-1245629. Epub 2010 Aug 19.
PMID: 20725881BACKGROUNDDewey M, de Vries H, de Vries L, Haas D, Leidecker C. The present and future of cardiac CT in research and clinical practice: moderated discussion and scientific debate with representatives from the four main vendors. Rofo. 2010 Apr;182(4):313-21. doi: 10.1055/s-0029-1245195. Epub 2010 Mar 16.
PMID: 20234975BACKGROUNDDewey M, Zimmermann E, Deissenrieder F, Laule M, Dubel HP, Schlattmann P, Knebel F, Rutsch W, Hamm B. Noninvasive coronary angiography by 320-row computed tomography with lower radiation exposure and maintained diagnostic accuracy: comparison of results with cardiac catheterization in a head-to-head pilot investigation. Circulation. 2009 Sep 8;120(10):867-75. doi: 10.1161/CIRCULATIONAHA.109.859280. Epub 2009 Aug 24.
PMID: 19704093RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marc Dewey, MD
Charité
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
July 23, 2008
First Posted
July 25, 2008
Study Start
April 1, 2008
Primary Completion
December 1, 2008
Study Completion
December 1, 2008
Last Updated
June 23, 2011
Record last verified: 2009-02