Epidemiology of Depression, Anxiety, and Cognitive Impairment

NCT00717041 | Completed Results

• 2 other identifiers: RSRB 24085NIH 5K23AG028942
• Study Type: observational
• Target: 1,206
• Locations: 1 country
• Sites: 1

Brief Summary

Many older adults have undetected health problems and lack basic prevention measures. Failure to identify and treat these conditions can lead to unnecessary morbidity and mortality and a decreased quality of life. Traditional screening and intervention programs, usually based in primary care providers' offices, have been insufficient, particularly in medically underserved populations. Alternate sites for screening and intervention have begun to receive attention and may hold promise. The emergency department (ED) is the entry point for access to medical and social services for many patients and has the potential to serve as a site to identify older adults with unmet needs. However, we do not know the prevalence of depression and cognitive impairment and how they differ by mode of arrival of the patient to the ED. Second, a question remains as to the validity of screening patients during an acute illness. Upon completion, this study will describe the epidemiology of the population of older adults presenting to the ED.

Conditions

Depression; Anxiety; Cognitive Impairment

Keywords

Depression; Anxiety; Cognitive Impairment; Emergency medicine; prehospital care

Outcome Measures

Primary Outcomes (3)

• Participants With Depression by Patient Health Questionnaire - 9

  Number of participants with depression as measured by the Patient Health Questionnaire - 9, with a score of greater than or equal to 10.

  2 hours

• Participants With Cognitive Impairment by Six Item Screener

  Number of participants with cogintiive impairment as measured by the Six Item Screener, with greater than 2 questions incorrect

  2 hours

• Participants With Anxiety by Generalized Anxiety Disorder - 7

  Participants with anxiety as measured by the Generalized Anxiety Disorder - 7, with a score greater than or equal to 10.

  2 hours

Secondary Outcomes (1)

• Depression and Cognitive Impairment at 2 Weeks

  2 weeks

Study Arms (1)

Presenting to the ED

Patients who present to the ED

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All older adults arriving at participating hospital emergency departments to obtain emergency care.

You may qualify if:

• Age 60 and older
• Arrival at ED

You may not qualify if:

• Institutionalized

Sponsors & Collaborators

• University of Rochester: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

University of Rochester

Rochester, New York, 14646, United States

Location

MeSH Terms

Conditions

Depression; Anxiety Disorders; Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Mental Disorders; Cognition Disorders; Neurocognitive Disorders

Limitations and Caveats

* Single center, limited generalizability * Large proportion of individuals lost to follow up * ED visit may have heightened symptoms * Validity of instruments in the ED setting is unknown

Results Point of Contact

• Title: Manish N. Shah, MD MPH
• Organization: University of Rochester

manish.shah@rochester.edu

585-275-1198

Study Officials

• Manish N. Shah, MD MPH

  University of Rochester

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 14, 2008
• First Posted: July 16, 2008
• Study Start: May 1, 2008
• Primary Completion: September 1, 2008
• Study Completion: February 1, 2009
• Last Updated: June 15, 2015
• Results First Posted: June 15, 2015

Record last verified: 2015-06

Locations

US (1)