NCT00705562

Brief Summary

The objective of the study is to assess comparative gastrointestinal tolerance of normal term infants to various milk-protein infant formulas.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
190

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Jun 2008

Shorter than P25 for phase_2

Geographic Reach
1 country

15 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

June 24, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 26, 2008

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2008

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
Last Updated

January 5, 2009

Status Verified

January 1, 2009

Enrollment Period

4 months

First QC Date

June 24, 2008

Last Update Submit

January 2, 2009

Conditions

Outcome Measures

Primary Outcomes (1)

  • Gastrointestinal tolerance

    0-8 days of age until 28 days of age

Secondary Outcomes (1)

  • GI and intake parameters

    0-8 to 28 days of age

Study Arms (5)

1

EXPERIMENTAL

Experimental milk protein based infant formula with varying carbohydrate and protein source

Other: milk protein formulas, varying carbohydrate/protein sources

2

EXPERIMENTAL

Experimental milk protein based infant formula with varying carbohydrate and protein source

Other: milk protein formulas, varying carbohydrate/protein sources

3

EXPERIMENTAL

Experimental milk protein based infant formula with varying carbohydrate and protein source

Other: milk protein formulas, varying carbohydrate/protein sources

4

EXPERIMENTAL

Experimental milk protein based infant formula with varying carbohydrate and protein source

Other: milk protein formulas, varying carbohydrate/protein sources

5

EXPERIMENTAL

Experimental milk protein based infant formula with varying carbohydrate and protein source

Other: milk protein formulas, varying carbohydrate/protein sources

Interventions

ad lib for 0-8 days of age until 28 days of age

12345

Eligibility Criteria

AgeUp to 8 Days
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Healthy, term infants; singleton birth; 37-42 weeks of age; \>2490gms at birth; 0-8 days of age

You may not qualify if:

  • medications/foods/formulas affecting GI tolerance;adverse medical history with possible effect on tolerance or growth

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (15)

Global Clinical Investigation

Aventura, Florida, 33180, United States

Location

University of South Florida

Tampa, Florida, 33606, United States

Location

University of Iowa

Coralville, Iowa, 52241, United States

Location

Medical Associates Clinic

Dubuque, Iowa, 52002, United States

Location

Kentucky Pediatric Research

Bardstown, Kentucky, 40004, United States

Location

PediaResearch, Inc

Owensboro, Kentucky, 42301, United States

Location

University of Maryland

Baltimore, Maryland, 21201, United States

Location

Midwest Children's Health Research Institute, LLC

Lincoln, Nebraska, 68504, United States

Location

The Center for Human Nutrition

Omaha, Nebraska, 68105, United States

Location

MetroHealth Medical Center

Cleveland, Ohio, 44109, United States

Location

Pediatric Associates of Fairfield

Fairfield, Ohio, 45014, United States

Location

Ohio Pediatric Research Association

Huber Heights, Ohio, 45424, United States

Location

Institute of Clinical Research

Mayfield Heights, Ohio, 44124, United States

Location

Primary Physicians Research, Inc

Pittsburgh, Pennsylvania, 15241, United States

Location

West Virginia University

Morgantown, West Virginia, 26506, United States

Location

Study Officials

  • Steven Davis, PhD

    Abbott Nutrition

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

June 24, 2008

First Posted

June 26, 2008

Study Start

June 1, 2008

Primary Completion

October 1, 2008

Study Completion

December 1, 2008

Last Updated

January 5, 2009

Record last verified: 2009-01

Locations