NCT00703729

Brief Summary

The purpose of this study is to evaluate and compare clinical post-operative outcomes for patients using active cooling and compression device and those using ice bags and elastic wrap after acromioplasty or arthroscopic rotator cuff repair.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
58

participants targeted

Target at P25-P50 for not_applicable postoperative-pain

Timeline
Completed

Started Jun 2008

Longer than P75 for not_applicable postoperative-pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

June 19, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 23, 2008

Completed
6.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
9 months until next milestone

Results Posted

Study results publicly available

September 10, 2015

Completed
Last Updated

September 10, 2015

Status Verified

August 1, 2015

Enrollment Period

6.5 years

First QC Date

June 19, 2008

Results QC Date

July 15, 2015

Last Update Submit

August 10, 2015

Conditions

Outcome Measures

Primary Outcomes (8)

  • Patient Reported Pain on Day 0

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 1

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 2

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 3

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 4

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 5

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 6

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

  • Patient Reported Pain on Day 7

    Pain was measured using a visual analog scale (VAS) 10 cm in length, with "no pain" at the left side of the scale and "extreme pain" at the right side. Scores were measured to the closest millimeter for a 0-100 scale.

    1 day

Secondary Outcomes (7)

  • Use of Pain Medication on Day 1

    1 day

  • Use of Pain Medication on Day 2

    1 day

  • Use of Pain Medication on Day 3

    1 day

  • Use of Pain Medication on Day 4

    1 day

  • Use of Pain Medication on Day 5

    1 day

  • +2 more secondary outcomes

Study Arms (2)

Cold Compression (CC)

EXPERIMENTAL

The Game Ready device provides both active, continuous cold and intermittent, pneumatic compression to the post-op shoulder. The first group will use the Game Ready™ Device (CC) for one week following surgery and will use standard ice bags wrapped to the shoulder (IW) for the remainder of the study period.

Device: Cold Compression (CC)

Ice Wrap (IW)

ACTIVE COMPARATOR

The ice bag (IW)is secured to the shoulder using an elastic wrap. The second group will use standard ice bags wrapped to the shoulder (IW) for one week following surgery and will use the Game Ready™ Device (CC) for the remainder of the study period

Other: Ice Wrap (IW)

Interventions

The device is applied to the shoulder within 60 minutes of arrival to the recovery room following surgery. The device will be applied at one hour intervals (60 minutes on the shoulder, 60 minutes off) during waking hours for the first 72 hours after surgery. For the remainder of the study period, therapy will be applied for one hour treatments 2-3 times a day during waking hours.

Cold Compression (CC)

The ice bag is applied to the shoulder within 60 minutes of arrival to the recovery room following surgery. The ice bag is placed on the shoulder and the elastic wrap is used to hold the bag in place. The ice will be applied at one hour intervals (60 minutes on the shoulder, 60 minutes off) during waking hours for the first 72 hours after surgery. For the remainder of the study period, therapy will be applied for one hour treatments 2-3 times a day during waking hours.

Ice Wrap (IW)

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient has undergone unilateral Rotator cuff repair or Acromioplasty
  • Willing to sign a consent form
  • Able to follow study procedures

You may not qualify if:

  • Non-ambulatory
  • Participation in concurrent investigational protocol
  • Any bleeding coagulopathies
  • Raynaud's disease or other vasospastic hypersensitivity or circulatory syndromes
  • Hypertension (due to secondary vasoconstriction)
  • Compromised local circulation (including localized compromise due to multiple surgical procedures)
  • A history of vascular impairment (such as frostbite or arterial sclerosis)
  • Cold allergy (cold urticaria) or prior adverse reactions to cold application
  • Rheumatoid arthritis
  • Local limb ischemia
  • Paroxysmal cold hemoglobinuria
  • Cryoglobulinemia or any disease that produces a marked cold pressor response
  • Inflammatory phlebitis
  • Acute inflammations of the veins (thrombophlebitis)
  • Decompensated cardiac insufficiency
  • +12 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CU Sports Medicine

Boulder, Colorado, 80304, United States

Location

MeSH Terms

Conditions

Pain, PostoperativeShoulder Pain

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsArthralgiaJoint DiseasesMusculoskeletal Diseases

Limitations and Caveats

Some patients were removed from the trial due to non-compliance, most commonly for failing to complete the pain diaries. There is also some inherent recall bias in asking a patient to fill out a diary.

Results Point of Contact

Title
Dr. Eric McCarty
Organization
CU Sports Medicine

Study Officials

  • Eric C McCarty, MD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 19, 2008

First Posted

June 23, 2008

Study Start

June 1, 2008

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

September 10, 2015

Results First Posted

September 10, 2015

Record last verified: 2015-08

Locations