NCT00701922|Completed
Surveillance Study of Viral Infections Following Lung Transplantation
Season Surveillance Study of Viral Infections in Lung Transplant Recipients
Loading search results
Season Surveillance Study of Viral Infections in Lung Transplant Recipients
Sponsor study identifier
observational
388
1 country
1
Study Start
October 2005
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2007
Actual (reported)Study Completion
December 2007
Actual (reported)The present study was conducted to study the impact community acquired respiratory virus (CARV) infections in an outpatient setting on graft function of lung transplant recipients. The study was aimed to identify risk factors for CARV infections. The study was further intended to investigate an association of Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human adenovirus (HAdV) with the development of BOS and to identify risk factors for virus detection in blood.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2007
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 2005
Date type not reportedThis date has not been verified as actual or estimated.
December 2007
Actual (reported)December 2007
Actual (reported)June 17, 2008
Actual (reported)June 19, 2008
Actual (reported)Incidence of bronchiolitis obliterans syndrome
1 year
Incidence of acute rejection
1 year
Incidence of hospitalisation
1 year
Incidence of graft loss (death or re-do-transplantation)
2 year
lung transplant recipients in in a single-centre outpatient clinic
Hannover Medical School
Hanover, 30625, Germany
Khalifah AP, Hachem RR, Chakinala MM, Schechtman KB, Patterson GA, Schuster DP, Mohanakumar T, Trulock EP, Walter MJ. Respiratory viral infections are a distinct risk for bronchiolitis obliterans syndrome and death. Am J Respir Crit Care Med. 2004 Jul 15;170(2):181-7. doi: 10.1164/rccm.200310-1359OC. Epub 2004 May 6.
Kumar D, Erdman D, Keshavjee S, Peret T, Tellier R, Hadjiliadis D, Johnson G, Ayers M, Siegal D, Humar A. Clinical impact of community-acquired respiratory viruses on bronchiolitis obliterans after lung transplant. Am J Transplant. 2005 Aug;5(8):2031-6. doi: 10.1111/j.1600-6143.2005.00971.x.
Nasopharyngeal and oropharyngeal swabs bronchoalveolar lavage blood samples
Jens T Gottlieb, MD
Dpt. Pulmonary Medicine
Ilka Engelmann, MD
Dpt. Virology, MHH
388 participants (actual enrollment reported by the registry).
First Submitted
June 17, 2008
First Posted
June 19, 2008
Study Start
October 2005
Date type not reportedThis date has not been verified as actual or estimated.
Telecommunication Via Cell Phones During Post-Operative Treatment After Lung Transplantation
Contact the study team to confirm eligibility.
Milstone AP, Brumble LM, Barnes J, Estes W, Loyd JE, Pierson RN 3rd, Dummer S. A single-season prospective study of respiratory viral infections in lung transplant recipients. Eur Respir J. 2006 Jul;28(1):131-7. doi: 10.1183/09031936.06.00105505. Epub 2006 Mar 1.
Engelmann I, Welte T, Fuhner T, Simon AR, Mattner F, Hoy L, Schulz TF, Gottlieb J. Detection of Epstein-Barr virus DNA in peripheral blood is associated with the development of bronchiolitis obliterans syndrome after lung transplantation. J Clin Virol. 2009 May;45(1):47-53. doi: 10.1016/j.jcv.2009.02.005. Epub 2009 Mar 20.
Primary Completion
December 2007
Actual (reported)Study Completion
December 2007
Actual (reported)Last Updated
October 28, 2011
Record last verified: 2008-12
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: