Evaluation of Thoracic Tumors With 18F-FMT and 18F-FDG PET-CT A Clinicopathological Study

NCT00698373 | Completed

• 1 other identifier: Molecular FMT imaging
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

L-\[3-18F\]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for positron emission tomography (PET). The aim of this study was to determine whether PET-CT with 18F-FMT provides additional information for the preoperative diagnostic workup as compared with 18F-FDG PET. Tumor uptake of 18F-FMT was compared with several immunohistochemical markers including L-type amino acid transporter 1 (LAT1).

Conditions

Non-Small Cell Lung Cancer

Keywords

Fluorine-18-α-methyltyrosine,; Positron emission tomography,; Fluorine-18-fluorodeoxyglucose,; Lung cancer,

Study Arms (1)

1

PET study

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with indeterminate pulmonary nodule suspicious of lung cancer were eligible for this prospective study.

You may qualify if:

• Patients with indeterminate pulmonary nodule suspicious of lung cancer

You may not qualify if:

• Patients with other malignancies and those who had received cancer treatment within the past 5 years were excluded.

Sponsors & Collaborators

• Gunma University: lead
• J~pharma: collaborator

MeSH Terms

Conditions

Carcinoma, Non-Small-Cell Lung; Lung Neoplasms

Condition Hierarchy (Ancestors)

Carcinoma, Bronchogenic; Bronchial Neoplasms; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: June 12, 2008
• First Posted: June 17, 2008
• Last Updated: June 17, 2008

Record last verified: 2008-06