NCT00686348

Brief Summary

To assess the safety and effectiveness of Somatuline® Depot (lanreotide) Injection when administered by a health care professional (HCP), the patient, the patient's partner or parent/guardian as part of their routine acromegaly care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
260

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2008

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2008

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

May 27, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 29, 2008

Completed
7.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

January 11, 2019

Status Verified

January 1, 2019

Enrollment Period

7.5 years

First QC Date

May 27, 2008

Last Update Submit

January 10, 2019

Conditions

Keywords

acromegaly

Outcome Measures

Primary Outcomes (1)

  • Assess the safety & effectiveness, as measured by IGF-1 & GH levels, of Somatuline® Depot Injection when administered by a health care professional, the patient, the patient's partner or parent/guardian as part of their routine acromegaly care.

    2 - 4 years/patient

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with a clinical diagnosis of acromegaly

You may qualify if:

  • The patient must have a clinical diagnosis of acromegaly
  • The patient must be treated with Somatuline® Depot (including patients newly prescribed Somatuline® Depot)
  • The patient or legally authorized representative must be able to understand the protocol and give signed informed consent. Assent from the patient should also be obtained, where appropriate. Signed informed consent and assent must be obtained before any study-related activities are conducted.

You may not qualify if:

  • Symptomatic, untreated biliary lithiasis
  • Known hypersensitivity to somatostatin analogs or related compounds (e.g., octreotide)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ipsen

Basking Ridge, New Jersey, 07920, United States

Location

Related Publications (1)

  • Salvatori R, Gordon MB, Woodmansee WW, Ioachimescu AG, Carver DW, Mirakhur B, Cox D, Molitch ME. A multicenter, observational study of lanreotide depot/autogel (LAN) in patients with acromegaly in the United States: 2-year experience from the SODA registry. Pituitary. 2017 Dec;20(6):605-618. doi: 10.1007/s11102-017-0821-y.

Related Links

Biospecimen

Retention: SAMPLES WITHOUT DNA

Routine clinical laboratory assessments will be performed: GH and IGF-1

MeSH Terms

Conditions

Acromegaly

Condition Hierarchy (Ancestors)

Bone Diseases, EndocrineBone DiseasesMusculoskeletal DiseasesHyperpituitarismPituitary DiseasesHypothalamic DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesEndocrine System Diseases

Study Officials

  • Ipsen Medical Director

    Ipsen (formerly Tercica, Inc.)

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 27, 2008

First Posted

May 29, 2008

Study Start

May 1, 2008

Primary Completion

November 1, 2015

Study Completion

November 1, 2015

Last Updated

January 11, 2019

Record last verified: 2019-01

Locations