Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

17.2%

65 terminated/withdrawn out of 378 trials

Success Rate

79.0%

-7.5% vs industry average

Late-Stage Pipeline

28%

107 trials in Phase 3/4

Results Transparency

48%

117 of 245 completed trials have results

Key Signals

38 recruiting117 with results51 terminated14 withdrawn

Enrollment Performance

Analytics

Phase 2
93(37.8%)
Phase 3
83(33.7%)
Phase 1
41(16.7%)
Phase 4
24(9.8%)
N/A
5(2.0%)
246Total
Phase 2(93)
Phase 3(83)
Phase 1(41)
Phase 4(24)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (378)

Showing 20 of 378 trials
NCT04526665Phase 3Active Not Recruiting

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)

Role: lead

NCT06850038Recruiting

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Role: lead

NCT07585097Recruiting

A Study to Observe the Long-term Safety of Odevixibat in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Role: lead

NCT07556913Recruiting

Elafibranor Pregnancy Surveillance Program: A Study to Evaluate the Safety of Elafibranor During Pregnancy

Role: lead

NCT06730061Phase 3Active Not Recruiting

A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)

Role: lead

NCT07191704Completed

A Study to Assess the Genetic Variations in Bile Flow Disorders: Linking Progressive Familial Intrahepatic Cholestasis (PFIC)-Related Genes to Symptoms in Adults With Recurrent Cholestasis in Spain

Role: lead

NCT06447168Recruiting

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

Role: lead

NCT05627362Phase 2Active Not Recruiting

A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.

Role: lead

NCT06016842Phase 3Recruiting

A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

Role: lead

NCT07588880Recruiting

A Study of the Effectiveness, Safety and the Long-term Outcomes of Participants With Progressive Familial Intrahepatic Cholestasis (PFIC) Who Take Odevixibat (Bylvay) in China

Role: lead

NCT07497724Active Not Recruiting

Odevixibat Outcomes in Patients With PFIC Versus an External Control Cohort (OvEC-PFIC)

Role: lead

NCT07387549Phase 3Recruiting

A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis

Role: lead

NCT07185919Recruiting

A Study of the Effectiveness, Safety and the Long-term Outcomes of Participants With Progressive Familial Intrahepatic Cholestasis (PFIC) Who Take Odevixibat (Bylvay) in South Korea

Role: lead

NCT06258902Recruiting

Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation

Role: lead

NCT03945773Phase 2Completed

Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors

Role: lead

NCT06305247Phase 1Active Not Recruiting

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

Role: lead

NCT07213830Phase 1Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Role: lead

NCT07441707Phase 1Recruiting

A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumours

Role: lead

NCT03647878Active Not Recruiting

Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment.

Role: lead

NCT04106349Active Not Recruiting

Observational Real-life Study of Cabozantinib in Monotherapy or in Combination With Nivolumab in Advanced Renal Cell Carcinoma (RCC)

Role: lead