Contingency Management for Smoking in Substance Abusers

NCT00683033 | Completed Phase 2

• 2 other identifiers: 08-081-2R21DA021836-01A2
• Study Type: interventional
• Target: 51
• Locations: 1 country
• Sites: 1

Brief Summary

Patients (N=102) who meet diagnostic criteria for alcohol, cocaine, marijuana, or opiate abuse or dependence will meet with research staff on two days for quit preparation sessions (2 per day). These sessions include testing a breath sample for evidence of smoking twice each day (separated by at least 5 hours), counseling based on Public Health Service (PHS) guidelines for quitting smoking during the second session each day, and setting a quit date. After these sessions, participants will be randomly assigned to one of two 4-week conditions: (a) standard care or (b) standard care plus prize CM for smoking abstinence with the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL). Nicotine withdrawal and related measures will be assessed throughout the intervention. Follow-up data will be collected through 6-months post-quit date.

Conditions

Cigarette Smoking

Keywords

Contingency Management; Cigarette Smoking Cessation; Substance Abusers

Outcome Measures

Primary Outcomes (1)

• Cigarette smoking abstinence.

  Daily through the 4-week intervention and at follow-up interviews 1, 2, 3, and 6 months following the quit date.

Study Arms (2)

A

ACTIVE COMPARATOR

Brief counseling based on public health service guidelines.

Behavioral: Brief smoking cessation counseling

B

EXPERIMENTAL

Brief counseling based on public health service guidelines for quitting smoking plus prize-based contingency management

Behavioral: Contingency Management; Behavioral: Brief smoking cessation counseling

Interventions

Contingency Management BEHAVIORAL

For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking is delivered. Expired carbon monoxide (CO) tests are conducted twice daily and urinary cotinine tests are conducted once each week. Participants earn the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL).

B

Brief smoking cessation counseling BEHAVIORAL

For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.

A; B

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• current alcohol, cocaine, marijuana, or opiate abuse or dependence
• smoke ≥ 10 cigarettes per day
• expired CO \> 8 ppm
• self-reported interest in quitting smoking,
• ≥ 18 years old
• willing to provide names, addresses and phone numbers of individuals to assist in locating the participant for follow-up evaluations,
• English speaking

You may not qualify if:

• currently receiving behavioral therapy or pharmacotherapy for smoking plan to use pharmacotherapy in this quit attempt
• serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk)
• cognitive impairment
• in recovery for pathological gambling

Sponsors & Collaborators

• UConn Health: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

University of Connecticut Health Center

Farmington, Connecticut, 06030, United States

Location

MeSH Terms

Conditions

Cigarette Smoking; Tobacco Use Cessation

Condition Hierarchy (Ancestors)

Tobacco Smoking; Smoking; Behavior; Tobacco Use; Health Behavior

Study Officials

• Sheila M Alessi, Ph.D.

  UConn Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 14, 2008
• First Posted: May 23, 2008
• Study Start: May 1, 2008
• Primary Completion: October 1, 2010
• Study Completion: October 1, 2010
• Last Updated: November 21, 2011

Record last verified: 2011-11

Locations

US (1)