Sentinel Surveillance of Malnutrition, Niger
Sentinel Surveillance of Acute Malnutrition in the Region of Maradi, Niger, Children Under 5: Impact of a Preventive Intervention
1 other identifier
interventional
N/A
0 countries
N/A
Brief Summary
Malnutrition is a critical public health problem in developing countries. Malnutrition may be linked to more than one half of the deaths in children under 5 years old. In July 2001, after an intervention related to a measles epidemic, Medecins sans Frontieres-France opened a nutritional program in Maradi, in the South of Niger. The introduction of ready to use therapeutic foods (RUTF), in particular Plumpy'Nut (Nutriset, France) allowed for the treatment of the majority of children at their homes using ambulatory treatment. Children with complicated cases were cared for in an inpatient center. With ambulatory treatment the number of children cared for in the MSF program reached close to 70000 in 2006. This study aimed to assess the effect of a 3-month distribution of RUTF in the context of a preventative supplementary feeding program. The primary hypotheses were that short-term RUTF supplementation at the village-level would prevent declines in weight-for-height and reduce the incidence of wasting in children 6 to 60 mo of age over a period of 8 mo. Because RUTF may have additional health effects, the intervention effect on height-for-age, stunting, mortality and morbidity from malaria, diarrhea, and respiratory infection were also examined.
Trial Health
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Started Aug 2006
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Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2008
CompletedFirst Submitted
Initial submission to the registry
March 26, 2008
CompletedFirst Posted
Study publicly available on registry
May 22, 2008
CompletedMay 22, 2008
May 1, 2008
1.6 years
March 26, 2008
May 21, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
weight-for-height in children 6 to 60 mo of age
8 months
Interventions
Eligibility Criteria
You may qualify if:
- All children resident in randomized villages 6-59 months
You may not qualify if:
- N/A
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Epicentrelead
- Ministry of Health, Nigercollaborator
- Medecins Sans Frontieres, Netherlandscollaborator
Related Publications (1)
Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, Guerin PJ, Grais RF. Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. JAMA. 2009 Jan 21;301(3):277-85. doi: 10.1001/jama.2008.1018.
PMID: 19155454DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Rebecca F Grais
Epicentre
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Purpose
- PREVENTION
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
March 26, 2008
First Posted
May 22, 2008
Study Start
August 1, 2006
Primary Completion
March 1, 2008
Study Completion
March 1, 2008
Last Updated
May 22, 2008
Record last verified: 2008-05