The Effect of Low Intensity Exercise on Quality of Life and Hemodynamics in Patients With Permanent Atrial Fibrillation

NCT00680290 | Terminated

• 1 other identifier: UTSW IRB 072004-047
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to 1) assess the effect of routine exercise on the quality of life of patients with permanent atrial fibrillation, and 2) assess the effect of exercise on cardio-hemodynamics in patients with atrial fibrillation.

Conditions

Atrial Fibrillation

Keywords

exercise, quality of life, cpx

Outcome Measures

Primary Outcomes (1)

• to 1) assess the effect of routine exercise on the quality of life of patients with permanent atrial fibrillation, and 2) assess the effect of exercise on cardio-hemodynamics in patients with atrial fibrillation.

  8 week

Study Arms (1)

1

EXPERIMENTAL

Exercise group

Procedure: Exercise

Interventions

Exercise PROCEDURE

Exercise x 8 weeks

1

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with permanent atrial fibrillation for at least three months duration, on stable medical therapy and in whom no additional interventions are planned to treat AF either due to clinical reasons or patient preferences
• Have the ability to understand and sign consent to participate and be willing and able to comply with prescribed exercise and schedule of evaluations
• Sedentary lifestyle as determined by Physical Activity Recall (PAR)
• Be greater than 18 years of age

You may not qualify if:

• Inability to exercise
• Functional Class IV CHF symptoms
• Active symptoms of angina, coronary artery disease
• Patient with recent history of myocardial infarction
• Patient with moderate or severely depressed left ventricular function (LVEF \< 40 %)
• Patient with any significant co-morbidities that may limit ability to exercise
• Patients already engaged a structured exercise program

Sponsors & Collaborators

• University of Texas Southwestern Medical Center: lead

Study Sites (1)

UT Southwestern Medical Center

Dallas, Texas, 75390, United States

Location

MeSH Terms

Conditions

Atrial Fibrillation; Motor Activity; Coproporphyria, Hereditary

Interventions

Exercise

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior; Porphyrias, Hepatic; Liver Diseases; Digestive System Diseases; Skin Diseases, Genetic; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin Diseases; Skin and Connective Tissue Diseases; Porphyrias; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Jose A Joglar

  University of Texas Southwestern Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 15, 2008
• First Posted: May 20, 2008
• Study Start: July 1, 2007
• Primary Completion: July 1, 2009
• Study Completion: July 1, 2009
• Last Updated: January 16, 2019

Record last verified: 2019-01

Locations

US (1)