NCT00667693

Brief Summary

This study will compare the Macintosh laryngoscope with the Pentax. The Pentax AWS is a novel airway management device that is designed to facilitate laryngoscopy and endotracheal intubation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
101

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Feb 2008

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2008

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

April 24, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 28, 2008

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2009

Completed
7.7 years until next milestone

Results Posted

Study results publicly available

October 31, 2016

Completed
Last Updated

July 24, 2018

Status Verified

July 1, 2018

Enrollment Period

1.1 years

First QC Date

April 24, 2008

Results QC Date

July 18, 2016

Last Update Submit

July 23, 2018

Conditions

Keywords

intubationobese

Outcome Measures

Primary Outcomes (1)

  • Time to Intubation

    time between sufficient muscle relaxant and placement of intubation tube

    time between sufficient muscle relaxant and placement of intubation tube, up to 100 seconds

Secondary Outcomes (4)

  • Ease of Intubation

    From the start of intubation until 24 hours after surgery

  • Successful Intubation on the First Attempt

    From the start of intubation until 24 hours after surgery

  • The Number of Patients With Different Number of Intubation Attempts

    From the start of intubation until 24 hours after surgery

  • The Number of Patients With Bleeding

    From the start of intubation until 24 hours after surgery

Study Arms (2)

Macintosh laryngoscope

ACTIVE COMPARATOR

Intubation with a Macintosh laryngoscope

Device: Macintosh laryngoscope

Pentax AWS

ACTIVE COMPARATOR

Intubation with a Pentax AWS

Device: Pentax AWS

Interventions

Intubation with Macintosh laryngoscope

Macintosh laryngoscope

Intubation with Pentax AWS

Pentax AWS

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • subject is at least 18 years old
  • BMI between 30 and 50
  • scheduled for elective surgery requiring orotracheal intubation

You may not qualify if:

  • a known difficult airway
  • loose teeth
  • subject pregnancy
  • rapid sequence induction required
  • subject is unable to give consent
  • anesthesiologist considered use of the Pentax AWS to be contraindicated
  • special endotracheal tube (ETT) is needed for the case.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cleveland Clinic

Cleveland, Ohio, 44195, United States

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Limitations and Caveats

It focused on obese patients; did not include patients with a history of difficult intubation; protocol did not include use of adjunctive devices; was impossible to blind the operator to the device being used; only the Mallampati score was recorded

Results Point of Contact

Title
Daniel I Sessler, MD
Organization
Cleveland Clinic Foundation

Study Officials

  • Daniel I Sessler, MD

    The Cleveland Clinic

    STUDY CHAIR
  • John Doyle, MD, PhD

    The Cleveland Clinic

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 24, 2008

First Posted

April 28, 2008

Study Start

February 1, 2008

Primary Completion

March 1, 2009

Study Completion

March 1, 2009

Last Updated

July 24, 2018

Results First Posted

October 31, 2016

Record last verified: 2018-07

Locations