NCT00663299

Brief Summary

To demonstrate performance of TRUFILL DCS and TRUFILL DCS ORBIT Detachable Coils in the treatment of aneurysms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
299

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2004

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2004

Completed
3.9 years until next milestone

First Submitted

Initial submission to the registry

April 17, 2008

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 22, 2008

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2009

Completed
Last Updated

May 17, 2012

Status Verified

May 1, 2012

Enrollment Period

4.9 years

First QC Date

April 17, 2008

Last Update Submit

May 15, 2012

Conditions

Keywords

Intracranial aneurysm

Outcome Measures

Primary Outcomes (1)

  • To demonstrate performance of TRUFILL® DCS and TRUFILL DCS ORBIT™ Detachable Coils in the treatment of aneurysms

    Between 3-6 months

Secondary Outcomes (1)

  • Adverse events and product complaints

    Ongoing throughout study

Study Arms (1)

Trufill Detachable Coil System

OTHER

There is only one treatment arm in the registry and it is all patients receiving treatment with Trufill Detachable Coil System. The use of bare platinum coils for the endovascular occlusion of cerebral aneurysms.

Device: Endovascular Embolization Device

Interventions

The TRUFILL DCS and TRUFILL DCS ORBIT Detachable Coils are each an embolic coil system that consists of a platinum detachable coil, a delivery system (delivery tube and coil introducer) and a syringe. Each system has been designed to deliver, position and detach embolic coils in order to embolize intracranial aneurysms

Also known as: TRUFILL® DCS and TRUFILL DCS ORBIT Detachable Coils
Trufill Detachable Coil System

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with angiographically documented aneurysms,
  • Either ruptured or unruptured,
  • Aneurysm deemed by the attending neurointerventionalist to be acceptable candidates for endovascular embolization

You may not qualify if:

  • \) Patient / Treatment outside of the approved labeling, indications for use.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kobe City General Hospital

Kobe, 650-0046, Japan

Location

Related Publications (1)

  • Hirsch JA, Bendok BR, Paulsen RD, Cognard C, Campos J, Cronqvist M. Midterm clinical experience with a complex-shaped detachable platinum coil system for the treatment of cerebral aneurysms: Trufill DCS Orbit detachable coil system registry interim results. J Vasc Interv Radiol. 2007 Dec;18(12):1487-94. doi: 10.1016/j.jvir.2007.07.020.

    PMID: 18057282BACKGROUND

MeSH Terms

Conditions

Intracranial Aneurysm

Condition Hierarchy (Ancestors)

Intracranial Arterial DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesAneurysmVascular DiseasesCardiovascular Diseases

Study Officials

  • Bernard Bendok, M.D.

    Northwestern University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 17, 2008

First Posted

April 22, 2008

Study Start

June 1, 2004

Primary Completion

May 1, 2009

Study Completion

May 1, 2009

Last Updated

May 17, 2012

Record last verified: 2012-05

Locations