NCT00659815

Brief Summary

The objective of the study is to evaluate the product performance of Bausch \& Lomb ReNu MultiPlus Multi-Purpose Solution in a new packaging configuration

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
312

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2008

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2008

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

April 12, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 16, 2008

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2008

Completed
2.5 years until next milestone

Results Posted

Study results publicly available

November 15, 2010

Completed
Last Updated

December 12, 2011

Status Verified

December 1, 2011

Enrollment Period

2 months

First QC Date

April 12, 2008

Results QC Date

September 7, 2010

Last Update Submit

December 7, 2011

Conditions

Outcome Measures

Primary Outcomes (3)

  • Comfort

    Non-inferiority assessment of symptoms/complaints to rate solution comfort. Measurement based on 0-100 scale for each eye. Zero represented the least favorable rating and 100 represented the most favorable rating.

    Over-all follow-up visits from baseline to 1 month

  • Slit Lamp Findings

    Graded 0-4 where Grade 0=none; Grade 1=Trace; Grade 2=Mild; Grade 3=Moderate; Grade 4=Severe.

    Over-all follow-up visits from baseline to1 month

  • Lens Deposits

    Lens Deposits (All Eligible, Dispensed Eyes) Absent = deposit ratings of none or light; Present = deposit ratings of medium or heavy.

    Over-all study visits, baseline to 1-month

Study Arms (2)

ReNu in Currently Marketed Bottle

ACTIVE COMPARATOR

Bausch \& Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in the Currently Marketed Resin Bottle.

Device: Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in the Currently Marketed Resin Bottle.

ReNu in Clear Resin Bottle

EXPERIMENTAL

Bausch \& Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in a Clear Resin Bottle.

Device: Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in a Clear Resin Bottle.

Interventions

Daily care for contact lenses.

ReNu in Currently Marketed Bottle

Daily care for contact lenses

ReNu in Clear Resin Bottle

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is a habitual wearer of planned replacement soft contact lenses
  • VA correctable to 0.3 LogMar or better (driving vision)
  • Clear central cornea
  • Subject uses a lens care system on a regular basis

You may not qualify if:

  • Systemic disease affecting ocular health
  • Using systemic or topical medications
  • Wear monovision, multifocal or toric contact lenses
  • Any grade 2 or greater slit lamp findings

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

James Ferrari, OD

Rochester, New York, 14609, United States

Location

Results Point of Contact

Title
Gerard Cairns
Organization
Bausch & Lomb Incorporated

Study Officials

  • Gerard Cairns, PhD, MCOptom

    Bausch & Lomb Incorporated

    STUDY DIRECTOR
  • James Ferrari, OD

    James Ferrari, OD

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 12, 2008

First Posted

April 16, 2008

Study Start

March 1, 2008

Primary Completion

May 1, 2008

Study Completion

May 1, 2008

Last Updated

December 12, 2011

Results First Posted

November 15, 2010

Record last verified: 2011-12

Locations