Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment

NCT00658502 | Unknown

• 1 other identifier: FEMH97006
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Our study has three parts has three parts, and the main aim of the study is to find out if corneal hysteresis was associated with myopia or even a predictor of myopia poor control predictor:

• Part 1 of our study: patients with anisomeropia whose spherical equivalent refraction as measured by cycloplegic autorefraction between the two eyes differ greater than 1.5 D.
• Part 2 of our study: Minus spherical equivalent refraction as measured by cycloplegic autorefraction.
• Part 3 of our study: patients with minus spherical equivalent refraction as measured by cycloplegic autorefraction who are under regular atropine for the treatment of myopia;patients who are prescribed with atropine treatment are in need of myopia control instead of for research interest

Conditions

Myopia; Anisometropia

Outcome Measures

Primary Outcomes (1)

• axial length, corneal hysteresis

  3 month

Secondary Outcomes (1)

• Refractive error, visual acuity, , intraocular pressure, , and corneal thickness

  3 month

Study Arms (2)

1

2

Eligibility Criteria

• Age: 6 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

age under 25 year old with or without myopia

You may qualify if:

• Normal ocular health other than myopia or anisometropia
• In good general health with no history of prematurity or cardiac or significant respiratory diseases
• No allergy to atropine, tropicamide, proparacaine, and benzalkonium chloride
• No previous or current use of contact lenses, bifocals, progressive addition lenses
• No amblyopia or manifest strabismus, including intermittent tropia

You may not qualify if:

• presence of keratoconus or other corneal disease
• previous eye drops usage except Atropine
• major ocular surgery history (including refractive surgery, scleral buckle, glaucoma filtering, cornea transplant, cataract and vitreoretinal surgery)
• presence of other ocular conditions such as glaucoma, uveitis, or other ocular inflammatory or vitreoretinal diseases.

Sponsors & Collaborators

• Far Eastern Memorial Hospital: lead

Study Sites (1)

Far Eastern Memorial Hospital

Banqiao District, Taipei, 220, Taiwan

RECRUITING

MeSH Terms

Conditions

Myopia; Anisometropia

Condition Hierarchy (Ancestors)

Refractive Errors; Eye Diseases

Central Study Contacts

Shu-Wen Chang, MD

CONTACT

886-8966-7000; swchang@ntu.edu.tw

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: April 11, 2008
• First Posted: April 15, 2008
• Study Start: March 1, 2008
• Primary Completion: August 1, 2009
• Study Completion: August 1, 2009
• Last Updated: April 15, 2008

Record last verified: 2008-03

Locations

TW (1)