NCT00644462

Brief Summary

The PulmoTrack® 2010 with WIM-PC™ Technologies device, indicated for acoustic pulmonary function measurement that quantifies the presence of wheezing. This study was designed in order to evaluate the efficacy and safety of using the WIM-PC™ device for wheeze detection during dynamic bronchial situations in asthmatic adult.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2009

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 20, 2008

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 26, 2008

Completed
1.2 years until next milestone

Study Start

First participant enrolled

June 1, 2009

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

January 13, 2009

Status Verified

January 1, 2009

Enrollment Period

6 months

First QC Date

March 20, 2008

Last Update Submit

January 10, 2009

Conditions

Keywords

wheeze detection

Outcome Measures

Primary Outcomes (1)

  • Study success will be declared if one of the following is met: A correlation of at least 0.25 (R2=0.25) will be found between WR and FEV1 measurements; A correlation of at least 0.7 will be found between clinical parameter and WZ measurements.

    6 months

Secondary Outcomes (1)

  • Evaluation of the safety of using the PulmoTrack® 2010 with WIM-PC™ Technologies for wheeze detection. Safety will be established by lack of adverse events. Since this is a Non Significant Risk (NSR) device serious adverse events are not expected

    1 hour

Study Arms (2)

1

Asthmatic subjects

Device: PulmoTrack® 2010 with WIM-PC™ Technologies

2

Healthy subjects

Device: PulmoTrack® 2010 with WIM-PC™ Technologies

Interventions

wheeze detection during dynamic bronchial situations in infants

12

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

asthmatic subjects or healthy subjects

You may qualify if:

  • Asthmatic or healthy subjects;
  • Age 18 and up;
  • Not smoking for at the last two years;
  • Subject or subject's parents/guardian is able to comprehend and give informed consent for participation in the study.

You may not qualify if:

  • Chest burns;
  • COPD;
  • Pregnant or lactating;
  • Mechanically ventilatory;
  • Homodynamic instability;
  • Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months prior to screening;
  • Acute infection requiring intravenous antibiotics at the time of screening;
  • Uncontrolled bleeding and coagulation disorders;
  • Uncontrolled diabetes mellitus: IDDM or NIDDM;
  • HIV positive or any other immunosuppressive disorder;
  • Subject objects to the study protocol;
  • Concurrent participation in any other clinical study;
  • Physician objection.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bnei-Zion Medical Center

Haifa, 31048, Israel

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Noam Gavriely, Prof.

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

March 20, 2008

First Posted

March 26, 2008

Study Start

June 1, 2009

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

January 13, 2009

Record last verified: 2009-01

Locations