NCT00640653

Brief Summary

This study will develop and evaluate the effectiveness of culturally appropriate HIV/sexually transmitted disease risk-reduction interventions in reducing sexual risk behavior among young African-American adolescents.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
662

participants targeted

Target at P75+ for not_applicable hiv-infections

Timeline
Completed

Started Sep 2001

Typical duration for not_applicable hiv-infections

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2001

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2004

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2004

Completed
3.6 years until next milestone

First Submitted

Initial submission to the registry

March 19, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 21, 2008

Completed
9.7 years until next milestone

Results Posted

Study results publicly available

December 13, 2017

Completed
Last Updated

December 13, 2017

Status Verified

November 1, 2017

Enrollment Period

2.9 years

First QC Date

March 19, 2008

Results QC Date

September 23, 2015

Last Update Submit

November 15, 2017

Conditions

Keywords

Sexual BehaviorAbstinenceIntervention StudiesHIVSexually Transmitted InfectionTheory of Planned BehaviorHIV Seronegativity

Outcome Measures

Primary Outcomes (1)

  • Self-report of Ever Having Sexual Intercourse

    Self-reported sexual initiation during the follow-up period among participants who reported never having sexual intercourse at baseline.

    24 months post-intervention

Secondary Outcomes (4)

  • Self-reported Sexual Intercourse in the Past 3 Months

    Measured at baseline and 3, 6, 12, 18, and 24 months post-intervention

  • Self-report of Having Multiple Sexual Partners in the Past 3 Months

    Measured at baseline and 3, 6, 12, 18, and 24 months post-intervention

  • Self-reported Consistent Condom Use in the Past 3 Months

    Measured at baseline and 3, 6, 12, 18, and 24 months post-intervention

  • Self-report of Having Sexual Intercourse Without Using a Condom During the Past 3 Months

    Measured at baseline and3, 6, 12, 18, and 24 months post-intervention

Study Arms (5)

Abstinence-only

EXPERIMENTAL

Participants will receive the abstinence-only HIV/STD risk-reduction intervention.

Behavioral: Abstinence-only HIV/STD risk-reduction intervention

Safer-sex only

EXPERIMENTAL

Participants will receive the safer-sex-only HIV/STD risk-reduction intervention.

Behavioral: Safer-sex-only HIV/STD risk-reduction intervention

Comprehensive-long

EXPERIMENTAL

Participants will receive the 12-h long comprehensive HIV/STD risk-reduction intervention.

Behavioral: Long comprehensive HIV/STD risk-reduction intervention

Comprehensive-short

EXPERIMENTAL

Participants will receive the 8-h short comprehensive HIV/STD risk-reduction intervention.

Behavioral: Short comprehensive HIV/STD risk-reduction intervention

Health-promotion control

ACTIVE COMPARATOR

Participants will receive the health promotion control intervention.

Behavioral: Health promotion control intervention

Interventions

Participants will attend two sessions consisting of eight 1-hour modules that are designed to increase knowledge, motivation, and skill for practicing abstinence. The intervention is not an abstinence-until-marriage intervention; the target behavior is abstaining from sexual activity until later in life when the adolescent is more prepared to handle the consequences. The intervention does not contain inaccurate information, portray sex in a negative light, or employ a moralistic tone. It is not designed to affect condom use.

Also known as: Abstinence
Abstinence-only

Participants will attend two sessions consisting of eight 1-hour modules that are designed to increase knowledge, motivation, and skill for using condoms during sexual intercourse. The intervention is not designed to influence abstinence.

Also known as: Condom-use intervention
Safer-sex only

Participants will attend three sessions consisting of twelve 1-hour modules that are designed to increase knowledge, motivation, and skill for practicing abstinence and for using condoms if participants decide to be sexually active. The intervention consists of the safer-sex-specific content (4 hours), the abstinence-specific content (4 hours), and the general content that is common to both of the single-component interventions (4 hours).

Also known as: Abstinence and condom-use intervention, Abstinence-plus intervention
Comprehensive-long

Participants will attend two sessions consisting of eight 1-hour modules that are designed to increase knowledge, motivation, and skill for practicing abstinence and for using condoms if participants decide to be sexually active.

Also known as: Abstinence and condom-use intervention, Abstinence-plus intervention
Comprehensive-short

Participants will attend two sessions consisting of eight 1-hour modules that are designed to increase knowledge, motivation, and skill for avoiding cigarette smoking and for incorporating a healthful diet, aerobic exercise, and breast and testicular self-examinations. The control intervention will focus on reducing risk of heart disease, hypertension, diabetes, and certain cancers. The intervention provides a control for "Hawthorne effects" to reduce the likelihood that the HIV/STD interventions' effects can be attributed to group interaction and special attention.

Also known as: Chronic disease prevention intervention
Health-promotion control

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Grade 6 or 7 student at a participating school
  • Written parent or guardian consent to participate
  • Self-identifies as African American or black

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

Related Publications (2)

  • Jemmott JB 3rd, Jemmott LS, Fong GT. Efficacy of a theory-based abstinence-only intervention over 24 months: a randomized controlled trial with young adolescents. Arch Pediatr Adolesc Med. 2010 Feb;164(2):152-9. doi: 10.1001/archpediatrics.2009.267.

  • Zhang J, Jemmott JB 3rd, Jemmott LS. Mediation and moderation of an efficacious theory-based abstinence-only intervention for African American adolescents. Health Psychol. 2015 Dec;34(12):1175-84. doi: 10.1037/hea0000244. Epub 2015 Jul 27.

MeSH Terms

Conditions

HIV InfectionsSexually Transmitted DiseasesSexual Behavior

Interventions

Natural Family Planning Methods

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsBehavior

Intervention Hierarchy (Ancestors)

ContraceptionReproductive TechniquesTherapeutics

Limitations and Caveats

The data were based on self-reports, which can be inaccurate because of poor memory or socially desirability bias. The results may be limited to African American grade 6 and 7 students willing to take part in a health program on weekends.

Results Point of Contact

Title
Dr. John B. Jemmott III
Organization
University of Pennsylvania

Study Officials

  • John B. Jemmott III, PhD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Kenneth B. Clark Professor of Communication and Psychiatry

Study Record Dates

First Submitted

March 19, 2008

First Posted

March 21, 2008

Study Start

September 1, 2001

Primary Completion

August 1, 2004

Study Completion

August 1, 2004

Last Updated

December 13, 2017

Results First Posted

December 13, 2017

Record last verified: 2017-11

Locations