NCT00629044

Brief Summary

The aim of this study is to assess the implicitement of the cholesterol 24 S hydroxylase gene and the 24 S hydroxycholesterol in glaucoma and in age related macular degeneration.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
320

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2007

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2007

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 25, 2008

Completed
9 days until next milestone

First Posted

Study publicly available on registry

March 5, 2008

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2009

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2011

Completed
Last Updated

March 28, 2011

Status Verified

August 1, 2009

Enrollment Period

2 years

First QC Date

February 25, 2008

Last Update Submit

March 25, 2011

Conditions

Glaucoma

Outcome Measures

Primary Outcomes (1)

  • To know if cholesterol 24 S hydroxylase and 24 hydroxycholesterol are involve in Glaucoma and AMD

    2 years

Study Arms (3)

G

ACTIVE COMPARATOR
Biological: Assessing the blood level of cholesterol 24 S Hydroxylase

AMD

ACTIVE COMPARATOR
Biological: Assessing the blood level of cholesterol 24 S hydroxylase

Healthy subjects

ACTIVE COMPARATOR
Biological: assessing the blood level of cholesterol 24 S hydroxylase

Interventions

assessing the blood level of cholesterol 24 S hydroxylaseBIOLOGICAL

Comparison of venous blood level of Cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with Glaucoma and AMD and in healthy subjects.

G

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient with Glaucoma
  • Patient with AMD
  • Healthy patient

You may not qualify if:

  • All patients who use any treatment in order to maintain in normal value their blood cholesterol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ophthalmology Unit CHU Dijon

Dijon, Burgundy, 21000, France

Location

Related Publications (1)

  • Joffre C, Souchier M, Gregoire S, Viau S, Bretillon L, Acar N, Bron AM, Creuzot-Garcher C. Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye. Br J Ophthalmol. 2008 Jan;92(1):116-9. doi: 10.1136/bjo.2007.126144.

    PMID: 18156378BACKGROUND

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases

Study Officials

  • Catherine Creuzot-Gracher, MD, PhD

    CHU Dijon

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 25, 2008

First Posted

March 5, 2008

Study Start

November 1, 2007

Primary Completion

November 1, 2009

Study Completion

January 1, 2011

Last Updated

March 28, 2011

Record last verified: 2009-08

Locations

FR(1)