NCT00624429

Brief Summary

The Early Head Start program serves lower socioeconomic inner-city children from birth to 3 years. This population has a higher incidence of asthma due to increased exposures. The primary objective of this study is: To evaluate the effect of early identification of these high risk, inner-city asthmatic infants, age 1-3 years, and early treatment with pulmicort respules on asthma morbidity (asthma symptoms and use of rescue medications), infant pulmonary functions, and use of health care resources (unscheduled clinic visits, emergency room visits and hospitalizations). To obtain pilot behavior information using Carey Temperament Scale, Bitsea and expand to Itsea if indicated.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for phase_4 asthma

Timeline
Completed

Started Mar 2008

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 15, 2008

Completed
12 days until next milestone

First Posted

Study publicly available on registry

February 27, 2008

Completed
3 days until next milestone

Study Start

First participant enrolled

March 1, 2008

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2010

Completed
Last Updated

September 18, 2009

Status Verified

February 1, 2009

Enrollment Period

1.8 years

First QC Date

February 15, 2008

Last Update Submit

September 17, 2009

Conditions

Keywords

AsthmaChildren

Outcome Measures

Primary Outcomes (1)

  • FEV0.5

    2 months and 6 months into study

Secondary Outcomes (3)

  • emergency room visits

    number of visits from baseline to 2 months and 2 months to 6months of study

  • behavior scores

    measured at baseline, 2 months and 6 months

  • number of asthma exacerbations from baseline to 2 months and 2 months to 6 months

    6 months

Interventions

Budesonide respules 0.5 mg nebulized once a day for 4 months of the study.

Also known as: Pulmicort respules

Eligibility Criteria

Age12 Months - 36 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Children 12-36 months of age with a history of wheezing or airway reactivity responding to bronchodilators, or diagnosed with asthma by a physician.

You may not qualify if:

  • Children less than 12 months or greater than 36 months of age.
  • Children diagnosed with attention deficit disorder by a physician or psychologist.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Phoenix Children's Hospital

Phoenix, Arizona, 85016, United States

RECRUITING

MeSH Terms

Conditions

Asthma

Interventions

Budesonide

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

PregnenedionesPregnenesPregnanesSteroidsFused-Ring CompoundsPolycyclic Compounds

Study Officials

  • Peggy Radford, MD

    Phoenix Children's Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 15, 2008

First Posted

February 27, 2008

Study Start

March 1, 2008

Primary Completion

December 1, 2009

Study Completion

January 1, 2010

Last Updated

September 18, 2009

Record last verified: 2009-02

Locations