The Effect of Eating Pulses for 8 Weeks on Satiety and Metabolic Syndrome Risk Factors in Overweight Individuals

NCT00604448 | Completed

• 2 other identifiers: Pulse_Canada_481556UfT fund#: 481556
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

In 2004, almost 60% of adult Canadians were overweight or obese. This is a serious health concern due to the burden of common health risks associated with being overweight and obese, including increased blood sugar, blood lipids and blood pressure. Together these risks are known as metabolic syndrome. Obesity, the most common nutrition problem in Canada, can in many cases be treated through changes in our diet (what we eat and/or how much we eat). Pulses (beans, chickpeas, lentils and peas) when eaten on a regular basis may result in decreased health risks associated with being overweight and obese. The purpose of this study is to find out whether eating pulses (5 cups per week) results in improvements in metabolic syndrome risk factors. We also want to determine whether the consumption of pulses alters the levels of satiety hormones (hormones that make us feel hungry or full) in the blood. This study will have 50 participants.

Conditions

Obesity; Overweight

Keywords

pulses; beans; obesity; overweight; metabolic syndrome

Outcome Measures

Primary Outcomes (1)

• blood glucose, lipids and satiety hormones

  4 months

Secondary Outcomes (1)

• body weight, waist circumference and blood pressure

  8 weeks

Study Arms (2)

Pulse group

EXPERIMENTAL

a group receiving a meal with pulses (5 cups/week) for 8 weeks

Other: Dietary advise; Other: Diet enriched with a meal containing pulses

Energy-restricted group

EXPERIMENTAL

a group with a diet restriction of 500 kcal/day for 8 weeks

Other: Dietary advise; Other: Diet enriched with a meal containing pulses

Interventions

Dietary advise OTHER

Subjects in energy-restricted group will follow dietician advise to keep a conventional energy restriction diet.

Also known as: Energy-restricted group

Energy-restricted group; Pulse group

Diet enriched with a meal containing pulses OTHER

Subjects in pulse group will consume the commercially available pulses for 8 weeks

Also known as: Pulse group

Energy-restricted group; Pulse group

Eligibility Criteria

• Age: 35 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• overweight/obese adults
• body mass index: 27-35 kg/m2
• individuals not prescribed medications over the past 6 months that could interfere with the study outcomes (i.e. statins or metformin)

You may not qualify if:

• smokers
• those on an energy restricted diet
• breakfast skippers
• pregnant/lactating women

Sponsors & Collaborators

• University of Toronto: lead
• Mount Sinai Hospital, Canada: collaborator

Study Sites (1)

Leadership Sinai Centre for Diabetes, Mt. Sinai Hospital

Toronto, Ontario, M5G 1X5, Canada

Location

MeSH Terms

Conditions

Obesity; Overweight; Metabolic Syndrome

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases

Study Officials

• Harvey G. Anderson, Ph.D.

  University of Toronto

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: January 17, 2008
• First Posted: January 30, 2008
• Study Start: February 1, 2008
• Primary Completion: August 1, 2008
• Study Completion: December 1, 2009
• Last Updated: June 15, 2012

Record last verified: 2012-06

Locations

CA (1)