NCT00603694|CompletedDMC
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Sponsor study identifier
observational
1
1 country
1
Study Start
September 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2013
Actual (reported)Study Completion
December 2013
Actual (reported)Neurocognitive impairment as a result of gamma knife radiosurgery has not been well studied and is poorly understood. Radiosurgery to the base of skull for the treatment of benign and malignant disorders may consequently impair memory function. There is a need to evaluate changes in memory function that may be associated with such exposures. In this pilot study, we will investigate changes in hippocampal-dependent memory function in 10 patients receiving a low SRS dose to the hippocampus. We will also investigate such changes in a no-dose control group and a high-dose control group. This study will provide preliminary estimates of variance in memory changes associated with radiation exposure, and will then permit us to design future studies with the appropriate sample size justification.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2013
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 2007
Date type not reportedThis date has not been verified as actual or estimated.
January 16, 2008
Actual (reported)January 29, 2008
Actual (reported)December 2013
Actual (reported)December 2013
Actual (reported)(Experimental group): Receiving \> 2 Gy SRS to left hippocampus (n=10)
(Low-dose control group): Receiving \< 0.5 Gy SRS to left hippocampus (n=10)
(High-dose control group): Receiving whole brain PCI (n=10)
Patients who have consented to GK radiosurgery or cranial radiation.
Joey & Toby Tanenbaum Gamma Knife Centre, Toronto Western Hospital
Toronto, Ontario, M5T 2S8, Canada
1 participants (actual enrollment reported by the registry).
First Submitted
January 16, 2008
First Posted
January 29, 2008
Study Start
September 2007
Date type not reportedThis date has not been verified as actual or estimated.
Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia
Contact the study team to confirm eligibility.
Primary Completion
December 2013
Actual (reported)Study Completion
December 2013
Actual (reported)Last Updated
June 23, 2016
Record last verified: 2016-06
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Source: ClinicalTrials.gov.
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