NCT00595777

Brief Summary

To determine if the institutionalisation of a regular systematic approach to the assessment of pain in inpatient cancer units using the Edinburgh Pain Assessment Tool (EPAT©) leads to better control of pain than that achieved by usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,928

participants targeted

Target at P75+ for not_applicable cancer

Timeline
Completed

Started Dec 2007

Longer than P75 for not_applicable cancer

Geographic Reach
1 country

19 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2007

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 7, 2008

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 16, 2008

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2012

Completed
Last Updated

September 26, 2012

Status Verified

September 1, 2012

Enrollment Period

4.7 years

First QC Date

January 7, 2008

Last Update Submit

September 25, 2012

Conditions

Keywords

Institutional changeImproved pain management

Outcome Measures

Primary Outcomes (1)

  • The magnitude of change in pain scores at the 2 evaluation points measured by patient self-rating

    Maximum study duration is 9 days per patient

Secondary Outcomes (3)

  • Magnitude of change in BPI scores over the 2 evaluation points (includes impact on function)

    Maximum study duration is 9 days per patient

  • Patient satisfaction with attention to pain

    Maximum study duration is 9 days per patient

  • Global distress

    Maximum study duration is 9 days per patient

Study Arms (2)

1. Comparison

NO INTERVENTION

The centres allocated to the comparison group will continue to provide usual care only.

2. Experimental

EXPERIMENTAL

The EPAT package consists of an educational programme, which deals with the common barriers to effective cancer pain control and the bedside pain tool.

Behavioral: EPAT© Educational Package

Interventions

The EPAT package consists of an education programme, which deals with the known common barriers to effective pain control and the bedside pain tool. The pain tool is uniquely incorporated into the vital signs chart to enable a systematic approach to cancer pain assessment and review. EPAT consists of 2 steps: step 1 is a colour-coded pain assessment on the bedside vital signs chart. Patients with moderate or severe pain on step 1 will progress to to step 2, which helps to identify the aetiology of the pain, screening for opioid side effects and is linked via flags to simple management plans. The intervention will be delivered to the clusters randomised to the intervention, after collection of baseline data (pre-intervention data) on 50 patients.

2. Experimental

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Able and consent to complete a Brief Pain Inventory score
  • Aged over 18 years
  • Have a pain score equal to or greater than 4 out of 10 at first assessment point (within 24 hours of admission) and pain is cancer related
  • Are expected to be available for pain assessment at 3 days after admission

You may not qualify if:

  • Do not consent to take part in the study or who are too ill to take part, including those with severe mental health problems
  • Do not have cancer-related pain
  • Are under 18 years of age
  • Have a pain score of less than 4
  • Are not expected to be available for pain assessment at 3 days after admission

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (19)

Mount Vernon Cancer Centre

Northwood, Middlesex, United Kingdom

Location

Bristol Haematology and Oncology Centre

Bristol, Sommerset, BS2 8ED, United Kingdom

Location

Belfast City Hospital

Belfast, United Kingdom

Location

Queen Elizabeth Hospital

Birmingham, United Kingdom

Location

Addenbrookes Hospital

Cambridge, United Kingdom

Location

Velindre Hospital

Cardiff, United Kingdom

Location

The Western General Hospital

Edinburgh, United Kingdom

Location

Beaston Oncology Centre

Glasgow, United Kingdom

Location

Hull Royal Infirmary

Hull, United Kingdom

Location

St. James's Hospital

Leeds, United Kingdom

Location

Clatterbridge Centre for Oncology

Liverpool, United Kingdom

Location

The Royal Marsden Hospital

London, United Kingdom

Location

The Christie

Manchester, United Kingdom

Location

Freeman Hospital

Newcastle, United Kingdom

Location

City Hospital

Nottingham, United Kingdom

Location

Churchill Hospital

Oxford, United Kingdom

Location

Derriford Hospital

Plymouth, United Kingdom

Location

Southampton University Hospital

Southampton, United Kingdom

Location

The Royal Marsden Hospital

Sutton, United Kingdom

Location

Related Publications (1)

  • Fallon M, Walker J, Colvin L, Rodriguez A, Murray G, Sharpe M; Edinburgh Pain Assessment and Management Tool Study Group. Pain Management in Cancer Center Inpatients: A Cluster Randomized Trial to Evaluate a Systematic Integrated Approach-The Edinburgh Pain Assessment and Management Tool. J Clin Oncol. 2018 May 1;36(13):1284-1290. doi: 10.1200/JCO.2017.76.1825. Epub 2018 Mar 15.

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Marie Fallon

    University of Edinburgh

    STUDY DIRECTOR
  • Michael Sharpe

    University of Edinburgh

    STUDY DIRECTOR
  • Lesley Colvin

    University of Edinburgh

    STUDY DIRECTOR
  • Gordon Murray

    University of Edinburgh

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 7, 2008

First Posted

January 16, 2008

Study Start

December 1, 2007

Primary Completion

August 1, 2012

Study Completion

August 1, 2012

Last Updated

September 26, 2012

Record last verified: 2012-09

Locations