Corneal Topographer Fluorescein Patterns

NCT00584285 | Completed Results

• 1 other identifier: 200709737
• Study Type: observational
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to determine if corneal topography can be used to predict the fluorescein pattern of keratoconus lenses on the eye. A corneal topography image will be taken and the computer selected lens will be placed on the eye. After placement of the lens color photographs will be taken of the eye's fluorescein pattern and compared to the computer predicted pattern.

Conditions

Keratoconus

Outcome Measures

Primary Outcomes (1)

• Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns

  Comparison of fluorescein patterns of rgp contact lens. Bearing and elevation fluorescein patterns will be compared between the actual (photo) and theoretical (computer generated) fluorescein patterns using standard clinical means.

  Baseline first visit

Study Arms (1)

Corneal Topographer Fluorescein Patterns

Use corneal topography to evaluate fluorescein pattern of rgp contact lens. Used corneal topography to develop theoretical fluorescein patters on a virtual eye. Theoretical lens developed by the topographer was ordered to compare to the actual fluorescein pattern on the actual eye.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

18 yrs of age or older with diagnosis of keratoconus and contact lens wearer

You may qualify if:

• yrs of age or older with diagnosis of keratoconus and contact lens wearer

You may not qualify if:

• Noncommittant corneal disease or surgery Inability to capture topography measurement

Sponsors & Collaborators

• Christine Sindt: lead

Study Sites (1)

University of Iowa Hospitals and Clinics - Dept. of Ophthalmology

Iowa City, Iowa, 52242, United States

Location

Related Publications (5)

• Szczotka LB. Clinical evaluation of a topographically based contact lens fitting software. Optom Vis Sci. 1997 Jan;74(1):14-9. doi: 10.1097/00006324-199701000-00015.

  PMID: 9148262 BACKGROUND

• Jani BR, Szczotka LB. Efficiency and accuracy of two computerized topography software systems for fitting rigid gas permeable contact lenses. CLAO J. 2000 Apr;26(2):91-6.

  PMID: 10810939 BACKGROUND

• Rabinowitz YS, Garbus JJ, Garbus C, McDonnell PJ. Contact lens selection for keratoconus using a computer-assisted videophotokeratoscope. CLAO J. 1991 Apr;17(2):88-93.

  PMID: 2049828 BACKGROUND

• Szczotka LB. Corneal topography and contact lenses. Ophthalmol Clin North Am. 2003 Sep;16(3):433-53. doi: 10.1016/s0896-1549(03)00054-3.

  PMID: 14564765 BACKGROUND

• Bufidis T, Konstas AG, Mamtziou E. The role of computerized corneal topography in rigid gas permeable contact lens fitting. CLAO J. 1998 Oct;24(4):206-9.

  PMID: 9800058 BACKGROUND

MeSH Terms

Conditions

Keratoconus

Condition Hierarchy (Ancestors)

Corneal Diseases; Eye Diseases

Results Point of Contact

• Title: Dr. Christine W. Sindt
• Organization: University of Iowa

christine-sindt@uiowa.edu

319-356-2916

Study Officials

• Christine W. Sindt, OD

  University of Iowa

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Asscociate Professor

Study Record Dates

• First Submitted: December 21, 2007
• First Posted: January 2, 2008
• Study Start: September 15, 2007
• Primary Completion: September 4, 2009
• Study Completion: September 14, 2009
• Last Updated: November 2, 2018
• Results First Posted: November 2, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)