Sponsor study identifier
Secondary identifiers
interventional
30
1 country
1
Study Start
January 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
December 2008
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Effective Treatment of PTSD involves talking about the traumatic event in detail.It is unclear how this process influences the sensory-specific trauma network (fear structure)in the traumatized person. The goal of the project is to test the hypothesis that treatment-facilitated recovery does not change the original fear structure but establishes an inhibitory mechanism that depends on verbal activity. An affective visual steady-state paradigm in magnetencephalography (MEG) using positive, aversive and neutral picture stimuli will be used to examine the spatial and temporal pattern of the processing of emotional stimuli. To examine the effects of treatment this paradigm will be used as outcome measure within a randomized controlled trial of Narrative Exposure Therapy and a waiting-list control condition for severely traumatized torture victims.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2008
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2007
Date type not reportedThis date has not been verified as actual or estimated.
November 23, 2007
Actual (reported)November 26, 2007
Actual (reported)December 2008
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)
4 & 9 months after completion of treatment
steady state visual evoked magnetic fields in response to affective stimuli
4 & 9 months after completion of treatment
Narrative Exposure Therapy (NET)
Waitinglist Control Group
Narrative Exposure Therapy for traumatized survivors of organized violence
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
University of Konstanz, Department of Psychology
Konstanz, 78467, Germany
Adenauer H, Catani C, Gola H, Keil J, Ruf M, Schauer M, Neuner F. Narrative exposure therapy for PTSD increases top-down processing of aversive stimuli--evidence from a randomized controlled treatment trial. BMC Neurosci. 2011 Dec 19;12:127. doi: 10.1186/1471-2202-12-127.
Adenauer H, Pinosch S, Catani C, Gola H, Keil J, Kissler J, Neuner F. Early processing of threat cues in posttraumatic stress disorder-evidence for a cortical vigilance-avoidance reaction. Biol Psychiatry. 2010 Sep 1;68(5):451-8. doi: 10.1016/j.biopsych.2010.05.015.
Claudia Catani, Dr.
University of Konstanz
Frank Neuner, Prof.
University of Konstanz
First Submitted
November 23, 2007
First Posted
November 26, 2007
Study Start
January 2007
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
December 2008
Estimated (date passed)Prevention of Posttraumatic Stress Disorder (PTSD) With Early Hydrocortisone Treatment: Pilot
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
November 26, 2007
Record last verified: 2007-11
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Source: ClinicalTrials.gov.
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