NCT00562679

Brief Summary

The purpose of this study is to determine the effect of sleep apnea on mortality, stroke and myocardial infarction among 408 patients with coronary artery disease referred for evaluation of coronary intervention who were examined with overnight cardio respiratory monitoring between March 1992 and June 1995.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
408

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 1992

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 1992

Completed
15.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2007

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 21, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 22, 2007

Completed
Last Updated

July 2, 2008

Status Verified

June 1, 2008

First QC Date

November 21, 2007

Last Update Submit

July 1, 2008

Conditions

Coronary Artery Disease

Keywords

Patients with coronary artery disease

Outcome Measures

Primary Outcomes (1)

  • Stroke, death, acute myocardial infarction

    10 years from date of inclusion

Study Arms (1)

2 groups

The cohort is grouped according to one group with sleep apnea and one group without sleep apnea

Other: There is no intervention

Interventions

There is no interventionOTHER
2 groups

Eligibility Criteria

AgeUp to 70 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patiens with coronary artery disease beeing referred for evaluation of coronary intervention

You may qualify if:

  • Men and women younger than 70 with disabling angina pectoris and coronary disease according to coronary angiography.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept of Cardiology

Umeå, SE 901 85, Sweden

Location

Related Publications (1)

  • Valham F, Mooe T, Rabben T, Stenlund H, Wiklund U, Franklin KA. Increased risk of stroke in patients with coronary artery disease and sleep apnea: a 10-year follow-up. Circulation. 2008 Aug 26;118(9):955-60. doi: 10.1161/CIRCULATIONAHA.108.783290. Epub 2008 Aug 12.

    PMID: 18697817DERIVED

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • Thomas Mooe, MD, PhD

    Dept Medicine, Östersund Hospital, Östersund

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 21, 2007

First Posted

November 22, 2007

Study Start

March 1, 1992

Study Completion

October 1, 2007

Last Updated

July 2, 2008

Record last verified: 2008-06

Locations

SE(1)