NCT00557414

Brief Summary

The purpose of this study is to determine the impact of the serum soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) on etiology and prognosis of acute respiratory distress syndrome (ARDS)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
63

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2007

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2007

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 12, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 14, 2007

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2008

Completed
Last Updated

May 13, 2008

Status Verified

May 1, 2008

First QC Date

November 12, 2007

Last Update Submit

May 8, 2008

Conditions

Acute Respiratory Distress Syndrome

Keywords

acute respiratory distress syndromesoluble triggering receptor expressed on myeloid cells-1prognosis

Outcome Measures

Primary Outcomes (2)

  • all cause mortality

    28 days

  • Septic or non-septic etiology

    At enrollment

Secondary Outcomes (2)

  • CRP, lactate, WBC count, APACHE II score, LIS, SOFA score

    At enrollment

  • IL-1 beta, IL-8, TNF-alpha

    serial follow up at Day 1, 3, 5, 7, 14

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients admitted into ICU of a medical center in Taiwan

You may qualify if:

  • Fulfill clinical diagnosis of ARDS
  • Require mechanical ventilation support

You may not qualify if:

  • Pregnant
  • Immunocompromised

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 100, Taiwan

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

serum

MeSH Terms

Conditions

Respiratory Distress Syndrome

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesRespiration Disorders

Study Officials

  • Chao-Chi Ho

    Department of Internal Medicine and Emergency Medicine, National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 12, 2007

First Posted

November 14, 2007

Study Start

October 1, 2007

Study Completion

March 1, 2008

Last Updated

May 13, 2008

Record last verified: 2008-05

Locations

TW(1)