Utility of Serial BNP Levels in Emergency Department CHF

NCT00534066 | Completed

• 1 other identifier: 2002H0262
• Study Type: observational
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to determine if a series of BNP blood tests performed on patients who present to the Emergency Department with congestive heart failure (CHF) can predict which patients may have adverse outcomes. If the BNP is shown to be predictive of bad outcomes in certain patients, those patients might receive more intensive therapy early to prevent such outcomes. This was a prospective trial enrolling patients who presented to the ED and were diagnosed with heart failure. Subjects had a blood test for BNP, which is elevated in the presence of heart failure, collected twelve hours after their initial clinical BNP was obtained in the ED. Demographics, history, length of hospital stay, and other approved data were collected. At 30 days and 6 months after discharge, a follow up call was made to determine if the subject had required additional emergency care, had been admitted to a hospital, or had died during that period of time.

Conditions

Congestive Heart Failure

Keywords

Natriuretic Peptide, Brain

Study Arms (2)

Admitted

Patients presenting to the ED with acute exacerbation of CHF who require admission to the hospital directly from the ED

Observational

Patients who present to the ED for acute exacerbation of CHF who are transferred to the Observation Unit from the ED for up to 24 hours.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age18 or older
• primary diagnosis of CHF in the Emergency Department
• admission to the hospital or transfer to the Observation Unit

You may not qualify if:

• minors, prisoners,pregnant women,unable to provide consent
• unstable angina or acute myocardial infarction in the ED
• dialysis dependent patients
• use of nesiritide as a therapy in the ED

Sponsors & Collaborators

• Ohio State University: lead

Study Sites (1)

The Ohio State University Medical Center

Columbus, Ohio, 43210, United States

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Officials

• Brian C Hiestand, MD

  Ohio State University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: DEFINED POPULATION
• Time Perspective: OTHER
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 21, 2007
• First Posted: September 24, 2007
• Study Start: September 1, 2002
• Study Completion: June 1, 2006
• Last Updated: September 24, 2007

Record last verified: 2007-04

Locations

US (1)