NCT00530049

Brief Summary

RATIONALE: Developing a questionnaire that patients can use to assess their quality of life related to the appearance of their face after surgery may help doctors plan the best treatment for patients undergoing surgery and reconstruction for head and neck cancer in the future. PURPOSE: This clinical trial is developing a questionnaire for assessing quality of life related to facial appearance in patients who have undergone or are planning to undergo surgery and reconstruction for head and neck cancer; and after dermatologic surgery for patients with cutaneous skin cancers.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,745

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2007

Longer than P75 for all trials

Geographic Reach
3 countries

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 14, 2007

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 13, 2007

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 17, 2007

Completed
14.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 17, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 17, 2021

Completed
Last Updated

December 21, 2021

Status Verified

December 1, 2021

Enrollment Period

14.4 years

First QC Date

September 13, 2007

Last Update Submit

December 20, 2021

Conditions

Keywords

psychosocial effects of cancer and its treatmenthypopharyngeal cancerlaryngeal cancerlip and oral cavity cancermetastatic squamous neck cancer with occult primarynasopharyngeal canceroropharyngeal cancerparanasal sinus and nasal cavity cancersalivary gland cancertongue cancer07-098

Outcome Measures

Primary Outcomes (1)

  • Development of patient-reported outcome measure of quality of life related to facial appearance

    2 years

Study Arms (1)

questionnaires

The purpose of this study is to develop a PRO instrument that measures quality of life as relates to facial appearance after head and neck cancer reconstruction surgery and after dermatologic surgery for patients with cutaneous skin cancers. . To develop this measure, we will adhere to the following sequential steps recommended by quality of life experts. Thus, the study will have three parts: * Questionnaire content generation and development of preliminary instrument * Field-testing the preliminary questionnaire with item reduction and development of final questionnaire * Psychometric evaluation of final questionnaire

Other: questionnaire administrationProcedure: assessment of therapy complicationsProcedure: psychosocial assessment and careProcedure: quality-of-life assessment

Interventions

questionnaires
questionnaires
questionnaires

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Potential research subjects will be identified by a member of the patient's treatment team, the protocol investigator, or research team at Memorial Sloan-Kettering Cancer Center (MSKCC), or specified plastic surgeon at outside institution.

You may qualify if:

  • Age 18 to 99 years.
  • Patients who have altered facial appearance secondary to an oncologic head and neck surgical resection and reconstruction. Reconstruction will be defined as complex linear closures, skin grafts, local flaps or free tissue transfer (oncologic Post-op cohort).
  • Patients who have undergone cosmetic plastic surgery procedures to the head and neck unrelated to a diagnosis of cancer (non-oncologic Post-op cohort).
  • Patients with cutaneous skin cancers of the head and neck region treated in the dermatologic surgery setting (dermatology Post-op cohort)
  • Patients who have completed surgery at MSKCC between 1 week to 7 years ago (Post-op cohorts).
  • Patients who have completed facial surgery 6 weeks (+/- 1 week) ago (early postoperative subset-Phase I).
  • Patients who are scheduled to undergo oncologic head and neck resection and reconstruction with anticipated altered facial appearance (Pre-op).
  • Patients who are scheduled to undergo dermatologic surgery due to diagnosis cutaneous skin cancers of the head and neck region (dermatology Pre-op cohort)

You may not qualify if:

  • Active psychiatric illness, cognitive or sensory impairment that in the opinion of the investigator is severe enough to preclude participation in the study.
  • Moderate to severe cognitive impairment.
  • Blindness.
  • Physical impairment that may prevent the respondent from filling out the paper and pencil survey.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

New School for Social Research

New York, New York, 10003, United States

Location

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States

Location

McMaster Children's Hospital at Hamilton Health Sciences

Hamilton, Ontario, L8N 3Z5, Canada

Location

University College of London Hospitals

London, England, WIT 3AA, United Kingdom

Location

Related Links

MeSH Terms

Conditions

Head and Neck NeoplasmsHypopharyngeal NeoplasmsLaryngeal NeoplasmsMouth NeoplasmsNasopharyngeal NeoplasmsOropharyngeal NeoplasmsSalivary Gland NeoplasmsTongue Neoplasms

Interventions

Psychiatric Rehabilitation

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsPharyngeal NeoplasmsOtorhinolaryngologic NeoplasmsPharyngeal DiseasesStomatognathic DiseasesOtorhinolaryngologic DiseasesLaryngeal DiseasesRespiratory Tract DiseasesRespiratory Tract NeoplasmsMouth DiseasesNasopharyngeal DiseasesSalivary Gland DiseasesTongue Diseases

Intervention Hierarchy (Ancestors)

RehabilitationTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Andrea L. Pusic, MD, MHS

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR
  • Peter G. Cordeiro, MD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 13, 2007

First Posted

September 17, 2007

Study Start

August 14, 2007

Primary Completion

December 17, 2021

Study Completion

December 17, 2021

Last Updated

December 21, 2021

Record last verified: 2021-12

Locations