NCT00515567

Brief Summary

The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
7mo left

Started Feb 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress97%
Feb 2006Dec 2026

Study Start

First participant enrolled

February 1, 2006

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

August 9, 2007

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 13, 2007

Completed
19.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

January 13, 2026

Status Verified

December 1, 2025

Enrollment Period

20.8 years

First QC Date

August 9, 2007

Last Update Submit

January 12, 2026

Conditions

Pulmonary Fibrosis

Keywords

explanted lungspulmonary fibrosis

Outcome Measures

Primary Outcomes (1)

  • assess fibroblasts and cytokines associated with pulmonary fibrosis

    12/2013

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects listed for lung transplant

You may qualify if:

  • all patients awaiting lung transplant

You may not qualify if:

  • all who will not give consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Chicago

Chicago, Illinois, 60637, United States

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

explanted lung tissue

MeSH Terms

Conditions

Pulmonary Fibrosis

Condition Hierarchy (Ancestors)

Lung Diseases, InterstitialLung DiseasesRespiratory Tract DiseasesFibrosisPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Nickolai Dulin, MD

    University of Chicago

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Nickolai Dulin, MD

CONTACT

ndulin@bsd.uchicago.edu

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 9, 2007

First Posted

August 13, 2007

Study Start

February 1, 2006

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

January 13, 2026

Record last verified: 2025-12

Locations

US(1)