DNA Array Analysis of Patients With Cervical Cancer
A Pilot Study of Early Changes in DNA Array Expression Following Chemo-Radiation Treatment of Cervical Cancer
1 other identifier
observational
18
1 country
1
Brief Summary
The goal of this clinical research study is to find out if the expression of certain genes is linked with the response of cervical cancer to radiation. Researchers will study a large number of genes located in tumor material to learn this information.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jun 2000
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 20, 2000
CompletedFirst Submitted
Initial submission to the registry
August 3, 2007
CompletedFirst Posted
Study publicly available on registry
August 7, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 20, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
November 20, 2017
CompletedNovember 30, 2017
November 1, 2017
17.4 years
August 3, 2007
November 28, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The goal of this clinical research study is to find out if the expression of certain genes is linked with the response of cervical cancer to radiation.
8 Years
Secondary Outcomes (1)
Researchers will study a large number of genes located in tumor material to learn this information.
8 Years
Study Arms (1)
Cervical cancer tumor biopsy + radiation therapy
Cervical cancer tumor biopsy + radiation therapy.
Interventions
Biopsies of the cervical tumor performed first before any treatment is given, and the second about 48 hours after radiation treatment has began.
Eligibility Criteria
Patients with cervical cancer already scheduled to begin radiation therapy.
You may qualify if:
- Newly diagnosed cervical cancer: clinical Stage IB -IIIB
- Invasive pure squamous cell carcinoma
- Planned treatment with concurrent cisplatinum/5-fluorouracil chemotherapy and pelvic radiation
You may not qualify if:
- \. Previous cervical cancer treatment including but not limited to transvaginal cone irradiation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
Related Links
Biospecimen
Two biopsies of the cervix will be performed to obtain tumor cells.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Anuja Jhingran, MD
M.D. Anderson Cancer Center
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 3, 2007
First Posted
August 7, 2007
Study Start
June 20, 2000
Primary Completion
November 20, 2017
Study Completion
November 20, 2017
Last Updated
November 30, 2017
Record last verified: 2017-11