Screening for Gynecologic Cancers in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients

NCT00508846 | Completed

• 1 other identifier: ID03-0211
• Study Type: observational
• Target: 93
• Locations: 1 country
• Sites: 1

Brief Summary

Among women with HNPCC, this study will assess:

1. 1.Knowledge of screening recommendations for endometrial and ovarian cancers.
2. 2.Perceived risk and cancer worries regarding endometrial, ovarian and colorectal cancers.
3. 3.Adherence to screening recommendations for endometrial, ovarian and colon cancers.
4. 4.Perceived benefits,supports and barriers to endometrial and ovarian cancer screening.
5. 5.Patterns of communication about endometrial and ovarian cancer risk within families with HNPCC and with health care providers.
6. 6.Patient preferences for potential cancer screening and cancer prevention strategies related to HNPCC-associated cancers.

Conditions

Colon Cancer

Keywords

Hereditary Non-Polyposis Colon Cancer; Gynecologic Cancers; Genetic Counseling; Questionnaire; Survey; HNPCC

Outcome Measures

Primary Outcomes (1)

• Patient Responses to Questionnaire

  Outcomes measuring demographics, surveillance behaviors, perceived risk, and cancer worries, screening supports/benefits and barriers.

  7 Years

Study Arms (1)

HNPCC Patients

Behavioral: Questionnaire

Interventions

Questionnaire BEHAVIORAL

Two-part telephone questionnaire lasting about 60 minutes total.

Also known as: Survey

HNPCC Patients

Eligibility Criteria

• Age: 25 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Women, age 25 years of age or older, diagnosed with Hereditary Non-Polyposis Colon Cancer (HNPCC).

You may qualify if:

• Being female
• Being 25 years of age or older
• Having an HNPCC-predisposing mutation and/or having a family history of cancer that meets the Amsterdam or Amsterdam II criteria for HNPCC

You may not qualify if:

• Persons who have tested negative for a known HNPCC-predisposing mutation in their family
• Persons who have no family HNPCC mutation and have not met the Amsterdam I/II criteria
• Being younger than 25 years old

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

• University of Texas MD Anderson Cancer Center Website

MeSH Terms

Conditions

Colonic Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Colorectal Neoplasms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Neoplastic Syndromes, Hereditary; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; DNA Repair-Deficiency Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Susan Peterson, PhD

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 26, 2007
• First Posted: July 30, 2007
• Study Start: May 1, 2003
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: March 11, 2016

Record last verified: 2016-03

Locations

US (1)