Evaluation of the French Version of Screening Questionnaires for Autism and Asperger Syndrome: AQ, EQ and SQ

NCT00505830 | Unknown

• 1 other identifier: Autisme AQ
• Study Type: observational
• Target: 450
• Locations: 1 country
• Sites: 1

Brief Summary

Autism is considered as an invading disorder of the development. Asperger Syndrome (AS) is a particular form of autism and is difficult to diagnose. The Autism Spectrum Quotient (AQ) has been developed in order to measure the degree of autistic traits in autistic adolescent with normal intelligence (Baron-Cohen et al. 2001, 2006). AQ comprises 50 questions, with 5 groups of 10 questions assessing imagination, social skills, attention switching, attention to detail and communication skills. Each of these items scores 1 point if the respondent records abnormal or autistic like behaviour. The minimum score on the AQ is 0 and the maximum 50. The principal objective of this study is to evaluate the accuracy of the French version of Autism Spectrum Quotient questionnaire. Secondary objectives are to: Evaluate if EQ and SQ can distinguish adolescents without psychiatric syndromes from those with classical autism or AS. Evaluate if AQ, EQ and SQ can distinguish adolescents with psychiatric disorders from autistic adolescents. Define the threshold of positivity for the 3 questionnaires.

Conditions

Asperger Syndrome; Autism

Keywords

Asperger Syndrom; Autism Quotient; French version; screening; diagnostic test; accuracy

Study Arms (4)

1

50 adolescents with AS or high functioning autism (HFS) diagnosed by psychiatrists using established criteria and with an IQ \>85.

Other: questionnaires

2

50 adolescents with AS or classical autism diagnosed by psychiatrists using established criteria 70\<IQ\<84.

Other: questionnaires

3

50 adolescents with psychiatric disorders but no autism syndrom.

Other: questionnaires

4

Sample of 50 healthy adolescents selected randomly from 200.

Other: questionnaires

Interventions

questionnaires OTHER

Primary outcome: Autism Spectrum Quotient (AQ) Secondary outcome measure: Empathy quotient (EQ) Systemizing quotient (SQ) WISC III or WISC IV ADOS score ADI score

1; 2; 3; 4

Eligibility Criteria

• Age: 12 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Group 1 (AS/HFA) and 2 (AS/classic autism) :
• Boys and girls aged 12 to 18
• Patients with autism or Asperger syndrome according to the diagnostic criteria (ICD 10)
• Patients receiving education in an ordinary school
• IQ\>70
• Group 3 (adolescents with psychiatric disorders):
• Boys and girls aged 12 to 18
• Patients hospitalized on a psychiatric ward or at a psychiatrics patient visit or psychiatric consultation wit hout autistic syndrome
• Patients receiving education in an ordinary school when not in hospital
• Group 4 (adolescent without psychiatric syndrome):
• Boys and girls aged 12 to 18
• Patients receiving education in an ordinary school

You may not qualify if:

• For all groups :
• Problem with language or comprehension
• Participants who have not given their consent

Sponsors & Collaborators

• Groupe Francais d'Epidemiologie Psychiatrique: lead
• Joint Clinical Research Center: collaborator

Study Sites (1)

Centre Hospitalier Saint Jean de Dieu

Lyon, France

RECRUITING

MeSH Terms

Conditions

Asperger Syndrome; Autistic Disorder

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Autism Spectrum Disorder; Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Sabine Manificat, MDH

  Centre Hospitalier Saint Jean de Dieu

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jean-Pierre Vignat, MDH

CONTACT

+33 4 37 90 11 75; jpvignat@ch-st-jean-de-dieu-lyon.fr

Study Design

• Study Type: observational
• Observational Model: DEFINED POPULATION
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: July 23, 2007
• First Posted: July 25, 2007
• Study Start: July 1, 2007
• Study Completion: July 1, 2009
• Last Updated: July 25, 2007

Record last verified: 2007-07

Locations

FR (1)