Sponsor study identifier
observational
450
1 country
1
Study Start
July 2007
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
July 2009
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Autism is considered as an invading disorder of the development. Asperger Syndrome (AS) is a particular form of autism and is difficult to diagnose. The Autism Spectrum Quotient (AQ) has been developed in order to measure the degree of autistic traits in autistic adolescent with normal intelligence (Baron-Cohen et al. 2001, 2006). AQ comprises 50 questions, with 5 groups of 10 questions assessing imagination, social skills, attention switching, attention to detail and communication skills. Each of these items scores 1 point if the respondent records abnormal or autistic like behaviour. The minimum score on the AQ is 0 and the maximum 50. The principal objective of this study is to evaluate the accuracy of the French version of Autism Spectrum Quotient questionnaire. Secondary objectives are to: Evaluate if EQ and SQ can distinguish adolescents without psychiatric syndromes from those with classical autism or AS. Evaluate if AQ, EQ and SQ can distinguish adolescents with psychiatric disorders from autistic adolescents. Define the threshold of positivity for the 3 questionnaires.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 2009
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2007
Date type not reportedThis date has not been verified as actual or estimated.
July 23, 2007
Actual (reported)July 25, 2007
Actual (reported)July 2009
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
50 adolescents with AS or high functioning autism (HFS) diagnosed by psychiatrists using established criteria and with an IQ \>85.
50 adolescents with AS or classical autism diagnosed by psychiatrists using established criteria 70\<IQ\<84.
50 adolescents with psychiatric disorders but no autism syndrom.
Sample of 50 healthy adolescents selected randomly from 200.
Primary outcome: Autism Spectrum Quotient (AQ) Secondary outcome measure: Empathy quotient (EQ) Systemizing quotient (SQ) WISC III or WISC IV ADOS score ADI score
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Centre Hospitalier Saint Jean de Dieu
Lyon, France
Sabine Manificat, MDH
Centre Hospitalier Saint Jean de Dieu
First Submitted
July 23, 2007
First Posted
July 25, 2007
Study Start
July 2007
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
July 2009
Estimated (date passed)Functional Magnetic Resonance Imaging (fMRI) for the Study of Response Inhibition, and Face and Linguistic Processing in Autism
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
July 25, 2007
Record last verified: 2007-07
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Source: ClinicalTrials.gov.
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