Cardiomyopathy Tissue Bank in a Cancer Population

NCT00500734 | Unknown

• 1 other identifier: ID02-359
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant. The goal of this laboratory research study is to collect and store blood and tissue from patients who have a diagnosis of heart disease and may be at a high risk for the development of heart failure. This blood may be used in the future to identify genes that may play a role in developing congestive heart failure (CHF) from chemotherapy or other sources. This is an investigational study. All will be enrolled at MD Anderson.

Conditions

Heart Disease

Keywords

Cardiomyopathy; Tissue Bank; Heart Disease; Heart Failure; Congestive Heart Failure

Outcome Measures

Primary Outcomes (2)

• Baseline Patient Demographic Information (age, sex, race)

  One time visit.

• Identification biological markers predisposing cancer patients to development of chemotherapy-induced congestive heart failure

  One time visit for collection of blood and tissue samples.

Study Arms (1)

Heart Disease Patients

Procedure: Blood Sample

Interventions

Blood Sample PROCEDURE

One time blood draw of 2 teaspoons.

Heart Disease Patients

Eligibility Criteria

• Age: 2 Months+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with heart disease and that may be at a high risk for the development of heart failure.

You may qualify if:

• Patients who are at high risk for developing Cardiomyopathy or Congestive Heart Failure.
• Patients two months of age and older.

You may not qualify if:

• Those that are not willing to sign an informed consent.

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

• University of Texas MD Anderson Cancer Center Website

Biospecimen

Retention: SAMPLES WITH DNA

Blood and tissue collection. This blood may be studied in the future to try to find possible genetic or biochemical markers that may be the cause of CHF.

MeSH Terms

Conditions

Heart Diseases; Cardiomyopathies; Heart Failure

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Officials

• Jean-Bernard Durand, MD

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jean-Bernard Durand, MD

CONTACT

713-792-6239; jdurand@mdanderson.org

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 12, 2007
• First Posted: July 13, 2007
• Study Start: December 10, 2002
• Primary Completion: December 1, 2020
• Study Completion: December 1, 2020
• Last Updated: January 27, 2020

Record last verified: 2020-01

Locations

US (1)