Catecholamines Can Attenuate Intermittent Hypoxia-Induced Expression of TNF in Human Monocytes
1 other identifier
observational
15
1 country
1
Brief Summary
Specific aim To examine the effect of catecholamines on the modulation of intermittent hypoxia induced TNF- in human monocytes from both healthy subjects and OSA patients (2). To map the signaling pathway of catecholamines regulating the intermittent hypoxia induced TNF- expression. (3). To explore the potential therapeutic effects of or agonists/antagonists on intermittent hypoxia induced TNF- expression
Trial Health
Trial Health Score
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participants targeted
Target at below P25 for all trials
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2006
CompletedFirst Submitted
Initial submission to the registry
July 8, 2007
CompletedFirst Posted
Study publicly available on registry
July 10, 2007
CompletedJuly 10, 2007
September 1, 2006
July 8, 2007
July 9, 2007
Conditions
Eligibility Criteria
You may qualify if:
- Healthy volunteer
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital
Taipei, 100, Taiwan
Study Officials
- PRINCIPAL INVESTIGATOR
Peiln Lee, M.D.
National Taiwan Univerisity Hospital
- PRINCIPAL INVESTIGATOR
Peilin Lee, M.D.
National Taiwan University Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- DEFINED POPULATION
- Time Perspective
- OTHER
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
July 8, 2007
First Posted
July 10, 2007
Study Start
September 1, 2006
Last Updated
July 10, 2007
Record last verified: 2006-09