NCT00451737

Brief Summary

The six-minute walk test had been used to assessment the cardiopulmonary parameter in patients with lung and heart disease. And it has good reliability and validity. It has been used extensively in research into the aerobic capacity in patients of peripheral vascular disease, neural system disease, and even the muscular-skeletal system disease, such as osteoarthritis, total hip or knee arthroplasty. There were studies investigate the predictors based on cardiopulmonary factors, neuromuscular and skeletal factors of the six-minute walk distance. But the last is the neuromuscular and skeletal factors. The purpose of this study is to investigate the correlations between the six-minute walk distance and neuromuscular parameters: muscle function (including muscle endurance, muscle strength and muscle power), knee proprioception, and standing balance. For that it could be more useful for evaluation and treatment patients in clinic. The study was planed to select 100 subjects, they are older than 65 years old with independent walking and without any diagnosis or symptoms about cardiopulmonary or neural disease. The evaluation are including knee proprioception (closed chain, active-active test), six-minute walk test, one leg standing balance test (open and close eyes for 30 seconds), quadriceps muscle strength at velocities of 600/s,1200/s and 1800/s, quadriceps muscle power at 1800/s, and quadriceps muscle endurance. To investigate the correlations between the six-minute walk distance and characteristics of subjects, the correlations between six-minute walk distance and neuromuscular parameters, including quadriceps muscle function (strength, endurance and power), knee proprioception, and one leg standing balance. And to analyze what's the most contribution to the six-minute walk distance.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P75+ for phase_1 healthy

Timeline
Completed

Started Nov 2006

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2006

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2007

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

March 22, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 23, 2007

Completed
Last Updated

March 23, 2007

Status Verified

January 1, 2006

First QC Date

March 22, 2007

Last Update Submit

March 22, 2007

Conditions

Keywords

Six-minute walk testNeuromuscular systemInfluence factors

Outcome Measures

Primary Outcomes (6)

  • six-minute walking test

  • knee joint reposition test

  • knee joint muscle strength

  • ankle joint muscle strength

  • knee joint muscle endurance

  • one leg standing balance

Interventions

Eligibility Criteria

Age65 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • older than 65 years old
  • independent walking

You may not qualify if:

  • diagnosis or symptoms about cardiopulmonary or neural disease
  • depression

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jan Mei Hwa

Taipei, Taiwan

RECRUITING

Study Officials

  • Jan Mei Hwa, MS

    kinesiology laborary of physical therapy in NTU

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 22, 2007

First Posted

March 23, 2007

Study Start

November 1, 2006

Study Completion

March 1, 2007

Last Updated

March 23, 2007

Record last verified: 2006-01

Locations